Neurological alterations pt 3 Flashcards

1
Q

(Cerebrovascular Accident - CVA)

Which term occurs when there is obstruction to arterial blood flow to the brain from thrombus formation, an embolus, or hypoperfusion related to decreased blood volume or heart failure, where the inadequate blood supply results in ___ (inadequate cellular oxygen) & can progress to __ (death of tissue)?

A

Ischemic stroke; ischemia; infarction

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2
Q

(Cerebrovascular Accident - CVA)

Which term refers to episodes of neurological dysfunction lasting no more than 1 hour and resulting from focal cerebral ischemia, with clinical manifestations including weakness, numbness, sudden confusion, loss of balance, or a sudden severe headache?

A

Transient ischemic attacks (TIAs)

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3
Q

(Cerebrovascular Accident - CVA) —> Ischemic stroke

Which term arises from arterial occlusions caused by thrombi formation in arteries supplying the brain or intracranial vessels, where conditions causing an increased ___ state increase the risk for thrombosis?

Which term involves fragments that break from a thrombus formed outside the brain, usually in the heart, aorta, or common carotid artery, and can also be from fat, air, tumour, bacteria, & foreign body; usually involving small brain vessels and obstructs at a bifurcation or other point of narrowing? Risk factors include, ___ __, left arterial or ventricle disease, recent myocardial infarction, & DVT

Which term refers to systemic ___ caused by __ __, cardiogenic shock, antihypertension medication?

A
  • Thrombotic stroke (cerebral thromboses); coagulation
  • Embolic stroke; artrial fibrillation
  • Hypoperfusion stroke; cardiac failure
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4
Q

(Cerebrovascular Accident - CVA) —> Ischemic stroke manifestations

Where manifestations can range from minimal – little or no symptoms to severe – hemiplegia, coma or death

In __ ___ their is a sudden onset – no history of claudication – may have cardiac abnormalities – comes from a ___ elsewhere in the body

In ___ ___ slow progression – history of claudication – might not have cardiac abnormalities – history of atherosclerosis

In ___ __ ___ symptoms are bilateral and diffuse

A
  • Embolic stroke; embolus
  • Thrombotic stroke
  • Hypoperfusion ischemic stroke
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5
Q

(Cerebrovascular Accident - CVA) —> Ischemic stroke manifestations

Manifestations are dependent on the __ _ __
, extent of damage done, extent of __ __ _ __

General signs & symptoms include: Headache, confusion, __, weakness or ___

A
  • Site of obstruction; collateral circulation that develops
  • Dizziness; paralysis
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6
Q

(Ischemic stroke treatment goals)

Which term is caused by vascular occlusion in brain, with irreversible ischemia & necrosis, where prompt infusion of thrombolytic agents may restore perfusion & prevent necrosis?

What are used to dissolve the clot- Ideally given within 3– 4.5 hours of event:
Such as streptokinase or t-PA?

Other goals of to treat ischemic stroke include:

Treatment goals for __ __ include preventing further ___ & anticoagulation therapy

A
  • Cerebral infarction
  • Thrombolytic medications
  • Control cerebral edema and the increased ICP, restoring brain perfusion, & controlling risk factors, such as smoking & hypertension
  • Embolic stroke; embolization
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7
Q

(CVA)

Which term refers to the 3rd most common cause of CVA, where bleeding causes compressed brain tissue, leading to ischemia, edema, and increased ICP and necrosis? It can occur within the brain tissue (intraparenchymal) or in the subarachnoid or subdural spaces

Bleeding can be ___, ___, or ___

A

Hemorrhagic stroke
- Massive; small; petechial

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8
Q

(Hemorrhagic stroke)

In the ___ the most common cause is hypertension & other causes, such as tumours, coagulation disorders, trauma, Drugs (cocaine)

In the ___ it is caused by aneurysms, arteriosclerosis malformations, or brain traumas

In the __ it is caused by brain traumas

A
  • Intraparenchymal
  • Subarachnoid
  • Subdural
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9
Q

(CVA)

The clinical manifestations of __ __ are similar to those for embolic & thrombotic stroke & depend on the __ & __ of the bleed. Symptoms can occur suddenly and with __.

In __ __ the person experiences 3 sets of symptoms:

(1) Excruciating generalized ___ –__ with consciousness maintained

(2) Sudden lapse into ___

& (3) If bleeding into brain tissue, hemiparesis or paralysis, __ may be present.

Also, stroke on right hemisphere shows deficits of __ __. However, if cranial nerves are affected – because cranial nerves never cross, the stroke on left side shows ___ ___deficits

A
  • Hemorrhagic stroke; location and size; activity
  • Headache
  • Unconsciousness
  • Dysphasia
  • Left side
  • left sided
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10
Q

(CVA)

Which term refers to the escape of blood from a defective or injured vessel into the subarachnoid space, where individuals at risk for this are those with intracranial aneurysm, intracranial AVM, hypertension, or a family history of ___, & those who have sustained head injuries? Also where mortality is 50% in 1 month

A

Subarachnoid hemorrhage (SAH)

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11
Q

(SAH)

___ __ result from defects in the vascular wall & are classified on the basis of __ & __. They are often __, but the signs vary depending on the __ & __ of the aneurysm

When a vessel is leaking, blood ___ into the subarachnoid space. When a vessel tears, blood under pressure is __ into the subarachnoid space, which increases __

An increase in ICP causes an increase in the __ __, which Impairs CSF __ & CSF ___

Similar to primary traumatic brain injury – intracranial volume– compressing and displacing brain tissue –decreased cerebral blood flow, edema, inflammation => increased ICP, & cell death

A
  • Intracranial aneurysms; form and shape; asymptomatic; location and size
  • Oozes; pumped; ICP
  • Intracranial volume; circulation; reabsorption
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12
Q

(SAH) –> Manifestations

Early includes – __, changes in mental status or LOC, nausea or __

A ruptured vessel causes – sudden __, “explosive” __ with nausea and vomiting, __ disturbances, __ deficits, decreased LOC, neck stiffness , __, & blurred vision due to meningeal irritation

A
  • Headache; vomiting
  • Throbbing; headache; visual; motor; photophobia
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13
Q

(CVA)
Which term refers to a rare congenital vascular lesion, & is a mass of dilated vessels instead of a capillary bed, characterized by abnormal structure, abnormally thin, complex growth & remodelling patterns of vessels?

Where signs & symptoms include: ..?

A

Arteriovenous malformation(AVM)
- Chronic headache & 50% will have seizures

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14
Q

(Outcomes of stroke) –> Which are dependent on __

Outcomes of stroke on __ ___ result in right sided weakness or paralysis,
problems with ___ (speaking & understanding),
__ __ (can’t see the right side of field of vision – both eyes), ___, impaired cognitive abilities, & memory problems

Outcomes of stroke on __ ___ result in left sided weakness or paralysis, denial of paralysis (reduced insight into condition, called “__ __” which is lack of response to stimuli on the left side), visual problems (can’t see the left side), depth perception problem, recognition of __ __, memory problems, depression, inappropriate behaviours, & impulsivity

Outcomes of stroke on the ___ result in problems with gait, dizziness, headache, nausea & vomiting

Outcomes of stroke on the ___ result in respiratory & cardiac concerns, temperature control, balance/coordination, weakness or paralysis, dysphagia, dysphasia, vision problems, & coma or death

A
  • Location
  • Left hemisphere; speech; visual problems; depression
  • Right hemisphere; left neglect; body parts;
  • Cerebellum
  • Brainstem (most dangerous)
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15
Q

(Outcomes of stroke)

Which term refers to to a disorder of attention that causes a person to have difficulty noticing, attending to, and responding to stimuli on the left side of their body. It typically occurs after damage to the brain’sright hemisphere?

A

Left neglect (a type of hemispatial neglect)

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16
Q

(Infections of the CNS)

Which term refers to an inflammation of the meninges of the brain or spinal cord, which can involve all 3 membranes (the dura mater, the arachnoid mater, & the pia mater), where tissues swell causing increased __ & reduced __ __ __; the mortality in untreated ___ is 70-100%?

If treated prognosis is good with rare complications

__ and __ __ are more at risk

A

Meningitis
- ICP; cerebral blood flow
- Infants & older adults

17
Q

(Infections of the CNS) –> Types of meningitis

The main cause or type of organism of meningitis is __ & __, but can also be due to fungi, parasites, or toxins.

Also classified as __, __, or __ – depending on the length of time it takes to develop:

__ - < 1 day
__ – 1-7 days
__ - > 7 days

A
  • Bacteria & viruses
  • Acute; subacute; chronic
  • Acute; subacute; chronic
18
Q

(Meningitis)

Which term has a rapid onset, and organisms vary with it, most commonly caused by the pathogens meningococci (Neisseria meningitidis) & pneumococci (Streptococcus pneumonia)?

The acute form is caused by streptococcus pneumonia, meningococcus, __, & ____

The chronic form is caused by __ & malignancies

A

Bacterial meningitis
- E. coli; H. influenzae
- Tuberculosis

19
Q

(Bacteria Meningitis) –>

Risk factors include..?

Invasive procedures include…?

Overcroded living conditions include..?

A
  • Invasive injury or procedure, respiratory/ear infection, immunocompromised individuals, & overcrowded living conditions
  • Lumbar puncture, craniotomy
  • Dormitories, army barracks
20
Q

(Meningitis) –> Manifestations

Which term result from direct infection or secondary to disease, such as enteroviral viruses, mumps, herpes type 2, measles; with mild symptoms & the disease is self limiting – managed with anti-viral medications?

Risk factors include: Infants, children, __ __, malnourishment, ___, & __ __

A

Viral meningits
- Older adults; immunosuppression; CNS trauma

21
Q

(Meningitis) –> Manifestations:

These manifestations can be grouped as __ signs, ___ signs, & __ signs

__ ___ include changes in LOC, focal deficits, & seizures

__ __ include fever, tachycardia, chills, etc…

__ __ include stiff neck, headache, photophobia, petechia, Kernig’s sign, & Brudzinski’s sign

A

Neurological signs; Infectious signs; clinical signs
- Same order as above

22
Q

(Meningitis) –> Diagnostics

Which term refers to severe stiffness of hamstrings causes an inability to straighten the leg when the hip is flexed to 90 degrees?

Which term refers to severe neck stiffness causes hips and knees to flex when the neck is flexed?

What shows elevated CSF pressure, where the CSF is sent for analysis?

A __ __ can look for signs of swelling, hemorrhage, or abscess – rule out hematoma, hemorrhage, or tumor

A
  • Kernig’s sign
  • Brudzinski’s sign
  • Lumbar puncture
    CT scan
23
Q

(Meningitis) –> Complication

In children includes:
__ __ (most common), epilepsy, ___ (accumulation of CSF in the brain), subdural ___ (fluid) subdural __ (pus), altered mental status, __ __, & intellectual deficit

A
  • Hearing loss; hydrocephalus; effusions; empyema; cerebrovascular damage,
24
Q

(Infection of the CNS)

Which term refers to an inflammation of the parenchyma of the brain or spinal cord due to infection, which is similar to ___ but patients are usually sicker with ___, where the virus invades the brain tissue & causes degeneration of the neurons; Caused by bacteria, virus, fungi, or parasites?

A

Encephalitis
- Meningitis

25
Q

(Encephalitis)

Manifestations include: Seizures, decrease __, aphasia, __, __ (__) __, __ (eye), hyperkinesia, & __ __ __

Potential complications include:
__ __, personality and behavior changes, __ problems, __, physical difficulties, __, fatigue

A
  • LOC; paralysis; ataxia (gait) abnormalities; nystagmus; severe personality changes
  • Memory problems; speech; epilepsy; depression;