Sara - Immunology Review Flashcards
What are the three main functions of the immune system?
Protection - defence from threats
Recognition of an antigen
Response to infection
List the four components of the immune system
Cells
Organs
Tissues
Immune cell products (cytokines and complement)
What are the two divisions of the immune system?
Innate
Adaptive
Give three characteristics of the innate immune system
No memory
Immediate response - initiated within seconds
Targets groups of pathogen - not specific
Give three characteristics of the adaptive immune system
Gradual response - over 3/4 days
Targets specific pathogens
Memory
What are the four barrier categories of innate immunity?
Anatomical e.g. skin
Physiological e.g. pH/body temp
Phagocytic e.g. macrophages
Inflammatory e.g. redness, pain etc
List the five main leukocytes
Neutrophils
Lymphocytes
Monocytes
Eosinophils
Basophils
What are mast cells also called?
Gatekeepers
What do mast cells release?
Inflammatory mediators
List four inflammatory mediators released by mast cells
Histamine
Prostaglandins
Leukotrienes
Cytokines
What are the two types of lymphocytes?
B and T lymphocytes
What cells need APCs for antigen recognition and activation?
T lymphocytes
What are the two types of T cell?
Helper = CD4+
Cytotoxic = CD8+
T Cells need an APC for activation, what are they called because of this?
MHC restricted cells
What immune cells are found in the lymph?
Dendritic cells
Lymphocytes
