Pharm - Exam 3 review Flashcards
Substance P is an excitatory substance that increases secretion and motility of the GI tract. Which part of the ANS is being supported by this action?
A - Parasympathetic
B - Sympathetic
A
Drugs that mimic the action of endogenous catecholamines are sympathomimetic drugs (adrenergic agonist). A direct-acting agonist helps reducing the metabolism of catecholamines.
A - True
B - False
B
What is the primary neurotransmitter released from preganglionic neurons at sympathetic/parasympathetic ganglionic sites?
A- NE
B - EPI
C - ACh
D - Neuropeptide Y
C
The anticipation of eating results in salivary secretion as response to a…
A - Sympathetic stimulation
B - Parasympathetic stimulation
B
Organophosphates are cholinesterase inhibitors and the poisoning can cause all of these actions except:
A - Profuse salivation
B - Severe bronchoconstriction
C - Relaxation of GI smooth muscle
D - Urination
C
Regarding to the use of NMB agents, which one of the following sentences is wrong?
A - These agents increase the muscle relaxation
B - An available apparatus for administering mechanical ventilation is always required
C - Some of them are eliminated by Hofmann elimination
D - Prior administration of sedation or tranquilization is not necessary
D
Metoclopramide is useful for the treatment of a GI-obstruction
A - True
B - False
B
Which of the following H2-receptor antagonists does have also a prokinetic action on GI-tract
A - Cimetidine
B - Ranitidine
C - Famotidine
B
Which of the following H2-receptor antagonists does have also a prokinetic action on GI-tract
A - Cimetidine
B - Ranitidine
C - Famotidine
D - It can cause reflux esophagitis
B
Pilocarpine is a parasympathomimetic agent. Which responses do you expect to see following the administration of pilocarpine?
A - Decreased of the peristaltic activity
B - Mydriatic effect
C - Increased of the IOP
D - Miosis Effect
D
Terbutaline, albuterol, clenbuterol are selective adrenergic agonist to receptor(s) …
A - Alpha-1
B - Beta-1
C - Alpha and beta 1
D - Beta-2
D
The vasoconstriction of blood vessel is a response to the stimulus of:
A - Isoproterenol
B - Dopamine
C - Phenylephrine
Phenylephrine
An individual endogenous catecholamine or sympathomimetic drug may exhibit a higher affinity or selectivity for one or more adrenergic receptor subtypes. EPI is one example of a very selective alpha-1 receptor agonist
A - True
B - False
False
Prokinetic drugs function to?
Increase the motility of the drug in the GI tract.
