123 - Infective Endocarditis Flashcards
(49 cards)
What is the typical sign of endocarditis?
vegetation
Endocarditis usually involve the cardiac __ and __
valves
ventricular septal defects
Infective endarteritis= vegetation of the: 3
arteriovenous shunts
arterio - arterio shunts
aortic coarctation
Endocarditis may be __ or __
acute
sub-acute
The main pathogens causing endocarditis are:4
strep Viridans
staphylococci
HACEK
strep bovis (gallolyticus) - from the GI
HACEK= _
Haemophilus Actinobacillus Cardiobacterium Eikenella Kingella
Health care NVE (__) is usually caused by: 3
native valve endocarditis
staph aureus
CoNS (Coagulase-negative staphylococci)
enterococci
Early PVE (__) is < __ days from surgery, late > _
prosthetic valve endocarditis
60
1 year
-% of endocarditis produce sterile cultures
5-15
NBTE=__, usually caused by __,__,__,__
non bacterial thrombotic endocarditis AR MR AS VSD
__ and __ can cause sterile vegetation
SLE
APLA
Which pathogens lead to ABE? 3
pneumococci
S aureus
B hemolytic strep
Which pathogens lead to SBE? 4
HACEK
CoNS
enterococci
strep viridans
Which pathogens lead to indolent bacterial endocarditis? 2
C burnetii
bartonella
(Q fever)
In ABE patients will experience high fever >__
In SBE patients will experience high fever in __ cases
39.5
rare
Cardiac clinical signs of IE include: 5
murmur CHF cardiac abscess AV block MI
Non cardiac clinical signs of IE include: 5
Osler's nodes Janeway's lesions Roth's spots musculoskeletal symptoms arterial thrombus
CNS clinical signs of IE include: 3
embolic stroke
microabscess
seizures/encephalopathy
Renal clinical signs of IE include: 2
Hypocomplementemic glomerulonephritis
pelvic pain and hematuria due to embolic thrombi
IE in IVDU usually involve the __ valve alone, together with __. __ might exist or not. Other general symptoms include: 3
tricuspid fever murmur cough pleuritic pain pneumothorax
If IE in IVDU affect the __/__ valve as well, we might notice pain on the __ side, like in non-IVDU
aortic
mitral
left
Which criteria is used to diagnose IE?
Duke’s criteria
According to Duke’s criteria-
Definite IE- _ major / _ major + _ minor / _ minor
Possible IE- _ major + _ minor / _ minor
2 major / 1 major +3 minor / 5 minor
1 major + 1 minor / 3 minor
We reject IE as a diagnosis if: 3
a different plausible diagnosis
symptoms resolve after 4 days of Abx
Unchanged biopsy after 4 days of treatment
