Benztropine

Question 1

Indication

Answer 1

-Parkinson’s disease
-Control extrapyramidal adverse effects except for tardive dyskinesia
-Acute dystonia reactions

Question 2

Mechanism of Action

Answer 2

Blocks acetylcholine action at cholinergic receptor sites. This restores the brain’s normal dopamine and acetylcholine balance which relaxes muscle movement and decreases drooling, rigidity, and tremor

Question 3

Contraindication

Answer 3

Hypersensitivity

Question 4

Interactions

Answer 4

TCA’s
Haloperidol- TD can worsen

Question 5

Side Effects

Answer 5

Side Effects

CNS: Agitation, confusion, delirium, delusions, sedation, paranoia, psychosis

CV: Bradycardia, ,
othostatic hypotension, palpitations

EENT: Blurred vision, dry mouth, increased ocular pressure

GI: Constipation, N/V

GU: Urinary hesitancy, urinary retention

MS: Muscle spasms

SKIN: Decreased sweating, flushing

Question 6

Life-threatening SE

Answer 6

CV: hypotension