Overdose or Poisoning

Question 1

what term refers to a collection of signs and symptoms that are observed after an exposure to a substance, “toxic fingerprint”

Answer 1

toxidrome

Question 2

dosage for naloxone

Answer 2

.4-2.0 every 2-3 min

Question 3

what is the most commonly used GI decontamination method and it’s dosage

Answer 3

activated charcoal
1 gm/kg

Question 4

what is the toxidrome for an anticholinergic

Answer 4

dry as a bone, red as a beet, hot as a hare, blind as a bat, mad as a hatter, and stuffed as a pipe

Question 5

what are some medications that cause the anticholinergic toxidrome

Answer 5

antihistamines (primarily diphenhydramine) phenothiazines, muscle relaxers, antidepressants, and Jimson Weed

Question 6

what are the clinical findings associated with inhibition of PNS? (anticholinergic)

Answer 6

absent bowel sounds, mydriasis, hyperthermia, dry skin/mucus membranes, urinary rentetionn, confusion/agitation, tachy, flushed skin

Question 7

what is the most common EKG finding with a anticholinergic overdose

Answer 7

sinus tachy. also, wide complex tachy and prolonged QT interval.

Question 8

what are the clinical features of serotonin syndrome

Answer 8

congnitive- confusion, agitation
autonomic- hyperthermia, diaphoresis, tachy
Neuromuscular- MYOCLONUS, hyperflexia, rigidity