Chapter 5 - Plasma Membrane Flashcards
What is the purpose of plasma membranes ?
- Compartmentalisation
- Regulate transport of materials
- Involved in cell signalling
What does the fluid mosaic model state ?
- Membranes are made of free to move phospholipids hence fluid
- Proteins are embedded within the membrane varying in size hence flexible
What is the structure of a phospholipid ?
What are the two structures formed by phospholipids ?
- Micelle
- Bilayer
Why are Micelles formed ?
Helps body absorb lipids, fats, and soluble vitamins
Encapsulates water
Why are Bilayers formed ?
Fatty acids are big and hurry to fit into interior of micelle
What are the factors that affect plasma membrane permeability ?
Temperature and solvents
How does temperature affect plasma membrane ?
As temp increases theres more kinetic energy, phospholipids move more.
This breaks structure
As temp decreases membrane stiffens, causes membrane to crack. This decreases fluidity which reduces permeability
What is put in place to prevent the effects of increase and decrease of temp on plasma membrane ?
[Increase]
Cholesterol helps prevent this as it holds bilayer together hence maintaining fluidity
[Decrease]
Unsaturated fatty acid tails have a kink that pushes away other phospholipids
Cholesterol also pushes through the phospholipids to prevent crunching
How do solvents affect plasma membranes ?
Some solvents such as ethanol can dissolve lipids which reduces bilayer stability and increases permeability
What is cholesterol ?
A lipid (sterol) with hydrophillic end and hydrophobic end positioned inbetween phopholipids
What is the function of cholesterol ?
- Adds stability by pulling phospholipids together; maintaining fluidity
What are the two types of membrane proteins ?
1) Intrinsic proteins
- Proteins that span the whole width of membrane
- Embedded within membrane
2) Extrinsic proteins
- Proteins confined to outer surface of membrane
What are the features of extrinsic proteins ?
- Act as receptors
- Involved in cell recognition
- Can dissociate from membrane
What are the examples of intrinsic proteins ?
- Channels proteins
(Act as a pore) - Carrier proteins
(Carry substances across membrane) - Glycoproteins
(Act as receptors) - Glycolipids
(Key in cell signalling, act as receptors for viruses)