JB-Infectious diseases Flashcards

1
Q

Treatment of amoebiasis (Entamoeba histolytica)

A

Metronidazole

Profuse bloody diarrhoea
Can cause liver accesses

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2
Q

Complication of amoebiasis (Entamoeba histolytica) infection

A

Liver access

RUQ pain and fever
Aspiration: “Anchovy sauce”

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3
Q

ABX for a dirty animal bite

A

co-amoxiclav

(doxycycline + metronidazole if pen allergic)

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4
Q

What is the most common cause of a Bacillus cereus infection

A

Food poisoning

Classically undercooked rice (incubation period of 1-6 hours)

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5
Q

Why are infants at risk of botulism (Clostridium botulinum) and what step is taken to reduce it

A

normal flora not developed and reduced levels of bile acids

Advise against honey until 12 months as natural reservoir

Named floppy baby syndrome

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6
Q

Most common cause of infectious diarrhoea in uk

A

Campylobacter

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7
Q

3 stages of Campylobacter infection

A

prodrome: headache

1-6 days incubation time

diarrhoea: often bloody
abdominal pain: may mimic appendicitis

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8
Q

Treatment for campylobacter infection

A

Usually not needed

Clarithromycin

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9
Q

Commonest protozoal cause of diarrhoea in the UK

A

Cryptosporidiosis

Mainly common in immunocompromised patients

Management supportive unless very unwell -> nitazoxanide/ rifaxime

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10
Q

CMV microscope appearance

A

Owl eyes (intranuclear inclusion bodies)

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11
Q

Features of congenital CMV

A

Growth retardation, pinpoint petechial ‘blueberry muffin’ skin lesions, microcephaly, sensorineural deafness, encephalitiis (seizures) and hepatosplenomegaly

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12
Q

Main risk factor for CMV retinitis

A

HIV with low CD4 count

Blurred vision with “pizza retina”
IV Gangciclovir

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13
Q

How is Dengue fever transmitted

A

Mosquitos (Aedes aegypti mosquito)

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14
Q

Main complication of Dengue

A

Severe dengue/ dengue haemorrhagic fever -> DIC

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15
Q

Dengue fever main symptoms

A

Sudden onset fever, headache, myalgia, rash

Facial flushing, haemorrhagic manifestations (tourniquet test, petechiae, epistaxis)

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16
Q

Dengue haematology and biochemistry results

A

Leukopenia, thrombocytopenia, raised aminotransferases

17
Q

4 Dengue warning signs

A

Abdominal pain
Hepatomegaly
Persistent vomiting
Fluid accumulation (ascites etc)

18
Q

Most common overgrowth organism in BV

A

Gardnerella vaginalis

19
Q

Diagnostic test for Lyme disease

A

Antibody titres for Borrelia burgdorferi

(Not PCR)

20
Q

Cardiac complications of Borrelia burgdorferi

A

Lyme disease

Heart block

21
Q

What population in leptospirosis seen in

A

sewage workers, farmers, vets or people who work in an abattoir

Travellers

From rat urine