Topic 25- Biological Chemistry Flashcards
Structure + properties of amino acid
Chiral
amphoteric
Carboxylic group
Amino group
Definition of a Zwitterion
A compound with no overall electric charge but with separate parts which are positively and negatively charged respectively
What does amphoteric mean
A substance which can act as an acid and a base at the same time
Why can enzymes only bind to one substrate
Their active site is stereospecific- only certain substrates are complementary to this
How does cisplatin work?
Ligand replacement reaction with DNA
A bond is formed between platinum and a nitrogen atom on guanine
Conditions for hydrolysis of proteins
Reflux + hot aqueous HCL
Draw the action of cis-platin
Structue of cis-platin
Structure of phosphate group
Structure of phosphate attached to ribose sugar
Why do different amino acids have different RF values
They have different polarities
Different affinities to stationary phase
Different solubility in mobile phase
