7.2 Flashcards

1
Q

Bone Matrix

A

*70% made of salts & most are called hydroxyapatite

*also includes collagen

*Ca2+ levels (homeostatic level) in the blood determine the formation and resorption of bone tissue

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2
Q

Low blood Ca2+

A

parathyroid hormone released that stimulates osteoclasts

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3
Q

High blood Ca2+

A

calcitonin released stimulating osteoblasts

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4
Q

Homeostasis in bone matrix

A

*collagen fibers add strength and resilience

*salts make bone hard

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5
Q

Compact Bone

A

*made up of osteons (Haversian system)

*In higher abundance in long bones & has no gaps in the matrix
-helps to resist compressive forces

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6
Q

Osteons

A

Cylinder-shaped units

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7
Q

Osteon Anatomy

A

*Central Canal
*Lamellae
*Lacunae
*Canaliculi
*Perforating Canals

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8
Q

Central Canal

A

Central tubular portion runs length (up and down) of the bone

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9
Q

Perforating Canals

A

*Transverse tubes that connect all central canals (run left to right)

*Allows for connection with the surface & medullary cavity

*Blood, lymph and nerve vessels from the periosteum penetrate the compact bone through this

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10
Q

Lamellae

A

Rings of hard calcified matrix laid down by osteoblasts

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11
Q

Lacunae

A

Spaces within the lamellae that contain osteocytes

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12
Q

Canaliculi

A

Small tubes in the extracellular matrix that connect osteocytes to each other and blood suppy

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13
Q

Spongy bone

A

*Does not contain true osteons
*No central canals, perforating canals, lamellae
*Does have lacunae and canaliculi
*Composed of Traveculae
*Most prevalent in short, flat and irregular bones
*Is also in the epiphysis of long bones

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14
Q

Trabeculae

A

Composed of branching, irregular bony plates

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15
Q

From superficial to deep (in diaphysis)

A

*periosteum
*compact bone
*endosteum
*spongy bone
*Medullary cavity

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16
Q

Factors affecting bone growth

A

*Deficiency of Vitamin A, C, D
*Insufficient growth hormone
*Excessive growth hormone
*Insufficient thyroid hormone
*Sex hormones
*Physical Stress

17
Q

Deficiency of vitamin A

A

Retarts bone development

18
Q

Deficiency of vitamin C

A

*Slows synthesis of collagen
*Results in fragile, slender bones
*Too much salt -> makes bone brittle

19
Q

Deficiency of vitamin D

A

*lack of ca2+ absorption (calcium)
*Insufficient growth hormone- loss of cartilage division
*Dwarfism (pituitary gland)

20
Q

Insufficient Thyroid hormone

A

*delays bone growth (diameter) calcitonin

21
Q

Sex hormones (Testosterome, estrogen, progestrone)

A

Promote bone formation; stop bone lengthening

22
Q

Physical stress

A

Stimulates bone growth