Clinical Microscopy Important People

Question 1

wrote a book in uroscopy

Answer 1

Hippocrates

Question 2

made the first description of hematuria as the presence of blood in the urine

Answer 2

Rufus of Ephesus

Question 3

• one of the founders of the origins of nephrology
• in his book Kitab al Baul, detailed the concepts of urine formation, urinary sediments, and urine characteristics in relation to diseases

Answer 3

Judaeus

Question 4

what year were color charts developed that described the significance of 20 different colors

Answer 4

1140

Question 5

chemical testing of urine for glucose involved?

Answer 5

ant testing and taste testing

Question 6

charlatans without medical credentials offered health-related predictions of patients using their urine samples

Answer 6

Pisse prophets

Question 7

• published a book that exposed the scam offered by the “pisse prophets”
• revelations uncovered in his book inspired the passing of the first medical licensure laws in England

Answer 7

Bryant

Question 8

• introduced the gravimetric analysis of urine by weighing a number of 24-hour urine specimens
• no significant conclusions were derived

Answer 8

van Helmont

Question 9

• discovered albuminuria by boiling urine
• observed that proteins in the urine precipitated when boiled with acetic acid

Answer 9

Dekker

Question 10

• first attempt to standardize the quantitation of formed elements in urine microscopic analysis
• Addis count: used a hemocytometer to count the number of RBCs, WBCs, casts and epithelial cells present in a 12-hour urine sample

Answer 10

Addis

Question 11

• urinalysis as part of a doctor’s routine patient examination
• revealed the presence of albumin in heated urine samples
• studied renal diseases and established the overall correlation of edema, albumin in urine, and diseased kidneys observed after death

Answer 11

Bright

Question 12

what year did urinalysis reach a point of impracticality, and urinalysis began to disappear in routine examinations?

Answer 12

1930s

Question 13

rescued routine urinalysis by making chemical and physical examination of urine samples easier

Answer 13

reagent strips (urine test strip)

Question 14

what year were urine test strips first made on industrial scale and offered commercially?

Answer 14

1950s

Question 15

what year did the company Boehringer Mannheim (today Roche) launch its first Combur test strips

Answer 15

1964