CV Drugs

Question 1

Ephedrine

____ mg

Typically, ____ mg diluted w/ __ cc NS or LR = ___ mg/mL

Answer 1

10 mg

50 mg in 4 cc (5 cc total)
10 mg/mL

Question 2

Phenylephrine

GTT: ____ mg in ____ mL NS or D5W = _____ mcg/mL (& can draw 10 cc syringe worth per patient)

BOLUS: mix ___ mg vial w/ ___ cc, empty to 1 cc. Draw up another 9 cc = _____ mcg/mL - bolus ___-____ mcg

Answer 2

10 mg in 250 cc = 40 mcg/mL (frequently put on micro gtt and titrated to effect)

10 mg w/ 10 cc
100 mcg/mL
50-100 mcg

Question 3

Vasopressin

20 Unit vial - dilute in ___ cc to ___ units/cc

Answer 3

10 cc
2 units/cc (bolus 0.5-1 unit)

Question 4

Epinephrine

Bolus: ___-____ mcg for moderate hypotension, ___-___ mg for circulatory collapse/pulseless

Infusion:
Low dose 0.01-0.03 mcg/kg/min (beta 2 dominant)
Mod dose 0.03-0.15 mcg/kg/min (beta 1 dominant)
Large dose >0.15 mcg/kg/min (beta + alpha 1, alpha 1 dominant)

Answer 4

10-100 mcg
1-3 mg

Question 5

Norepinephrine

Infusion:
__-___ mcg/min
____-____ mcg/kg/min (___ mg in ____ mL)
(low dose is beta 1 selective, high dose is alpha 1/beta 1 dominant - increases SVR/BP, decreases HR)

Bolus: ___-___ mcg diluted (less bradycardia than phenylephrine)

Answer 5

1-20 mcg/min
0.02-0.4 mcg/kg/min
4 mg in 250 mL

4-16 mcgs

Question 6

Dopamine

Low dose __-__ mcg/kg/min (D1 receptors)
Mod dose ___-___ mcg/kg/min (beta 1)
High dose ___-____ mcg/kg/min (alpha 1)

Answer 6

1-2
2-10
10-20

Question 7

Dobutamine

___-___ mcg/kg/min (beta 1&raquo_space; beta 2)

Answer 7

0.5-15 mcg/kg/min

Question 8

Milrinone (PDEI)

Infusion: bolus ____ mcg/kg, then ____ mcg/kg/min

Answer 8

50 mcg/kg
0.5 mcg/kg/min

Question 9

CaCl

____ mg-___ gram over 10 min (may dilute in 100 cc)

Answer 9

250 mg - 1 g

Question 10

Glucagon

___-____ mg IV

Answer 10

1-5 mg

Question 11

Metoprolol

Titrate to HR 60-80, SBP > 100 mmHg

Bolus ___ mg if HR >80, ___ mg if HR 60-80

Answer 11

5 mg
2.5 mg

Question 12

Esmolol

Bolus: ___-____ mg/kg

Laryngoscopy: _____ mg 2 min prior

Infusion: ___-_____ mcg/kg/min (2.5 g in 250 mL)

Answer 12

0.2-0.5 mg/kg

150 mg

50-200 mcg/kg/min

Question 13

Labetalol

Bolus: ____-_____ mg/kg

Infusion: 2-8 mg/min (200 mg in 200 cc)

Answer 13

0.1-0.5 mg/kg

Question 14

Nicardipine

Infusion: titrate starting at ___ mg/hr, increase by ___ mg/hr every 15 min to max of ___ mg/hr

____ mg in _____ mL
or ____ mg in _____ mL

Answer 14

5 mg/hr
2.5 mg
15 mg/hr

25 mg in 240 cc
50 mg in 250 cc

Question 15

SNP

Infusion: initial rate of ___-___ mcg/kg/min (max of ___ mcg/kg/min)

____ mg in _____ mL

Answer 15

0.25-1 mcg/kg/min, up to 2 mcg/kg/min

50 mg in 250 mL

Question 16

Nitroglycerin

Infusion up to ___ mcg/kg/min or ___-____ mcg/min

____ mg in _____ mL

Answer 16

2 mcg/kg/min
25-200 mcg/min

50 mg in 250 mL

Question 17

Hydralazine

Bolus: ___-___ mg (onset 10-20 min - consider 5 mg increments)

Answer 17

10-20 mg