Antimicrobial Targets By Category

Question 1

β-lactams (penicillis, cephalosporins, monobactams, carbapenems)

Answer 1

‘inhibition of cell wall synthesis by inhibiting PBPs

Question 2

Glycopeptides

Answer 2

inhibition of cell wall synthesis by inhibiting PG synthesis

Question 3

Aminoglycosides

Answer 3

inhibition of protein synthesis by inhibiting the 30s subunit of bacterial ribosome

Question 4

-Tetracyclines

Answer 4

inhibition of protein synthesis by inhibiting the 30s subunit of bacterial ribosome

Question 5

Oxazolidinones

Answer 5

inhibition of protein synthesis by inhibiting the 50s subunit of bacterial ribosome

Question 6

Macrolides, Ketolides and Lincosamides

Answer 6

. inhibition of protein synthesis by inhibiting the 50s subunit of bacterial ribosome

Question 7

Lipopeptides

Answer 7

. disruption of cytoplasmic membrane

Question 8

Polymyxins and Colistin

Answer 8

disruption of cytoplasmic membrane

Question 9

Quinolones

Answer 9

inhibition of nucleic acid synthesis by inhibiting enzymes DNA gyrase and topoisomerase IV

Question 10

Nitroimidazoles

Answer 10

inhibition of nucleic acid synthesis

Question 11

-Sulfonamides and trimethoprim

Answer 11

inhibition of folic acid synthesis