lecture 14 redone

Question 1

glutamate is a

Answer 1

excitatory neurotransmitter

Question 2

glutamate binds to

Answer 2

AMPARs and NMDARs in the body

Question 3

are NMDA receptors or AMPA receptors more sensitive

Answer 3

NMDA receptors

Question 4

example of NMDA receptor

Answer 4

GluN

Question 5

example of AMPA receptor

Answer 5

GluA

Question 6

kainate receptors

Answer 6

GluK

Question 7

ionotropic glutamate receptors are made up of _ subunits

Answer 7

4

Question 8

AMPAR subunits are

Answer 8

GluA1-4

Question 9

how does the flip variant affects the GluA channel

Answer 9

lengthens the time the channel is open for

Question 10

if the GluA2 is present is makes the receptor impermeable to

Answer 10

calcium

Question 11

what makes glua2 impermeable to calcium

Answer 11

glutamine (q) is swapped for argenine (r) which is positively charges repelling the calcium

Question 12

NMDA receptors are ______ permeable

Answer 12

calcium

Question 13

magnesium wedges itself into the pore, its drawn in due to the

Answer 13

negative field inside the membrane

Question 14

as the cell is depolarised theres less of a negative feild so the magnesium

Answer 14

is forced out and the pore opens

Question 15

NMDA receptors require the presense of

Answer 15

glutamate and require the cell to be depolarides to be open