DNA Flashcards

1
Q

What was already known about genes or what do you know

A

That they code genetic information and that its a generational molecule/s being passed down. One gene- one polypeptide. Chromosomes were available

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2
Q

Can you explain Griffith experiment with Virulent?

A

Talk about the 4 different processes with the Mice

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3
Q

Chromosomes are small enough to be transferred but which component, DNA or protein conferred virulence.

A

Hmmmm

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4
Q

Explain the experiment with RNase. Proase and DNase

A

Think about what was effected and what was not

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5
Q

What are phages

A

They are genetic material wrapped in protein. They are viruses that infect bacteria and use them to create more phage. Think about the influenza.

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6
Q

Explain Chargaff’s rule

A

yes

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7
Q

how is genteic info is stored in chromosomes

A

think about histones and condensing

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8
Q

Is mitosis started before DNA replication

A

NO! mitosis cannot occur without DNA replication

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9
Q

Explain why semi conservative is the right way of DNA also explain melelson strahl experiment

A

COOL

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10
Q

The series of DNA replication

A

topoisomerasre
helicase
single strand protiens
primase
DNA polymerase
DNA ligase

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11
Q

what is the ori

A

the segments where DNA gets replicationed multiple sites

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12
Q

The difference between eurkayotic and prokaryotic DNA replication

A

nice

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13
Q

What is the finishing problem

A

Where telomerase comes in but why

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14
Q

Errors in disease happen how?

A

A mutation or inactive enzyme that can change the product

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15
Q

Neurospora mold experiment

A

Hypothesis - each gene determines on enxyme in a biochemical pathway. Explain the order and what is needed for growth to occur

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16
Q

what does the one gene and one enzyme have to do with mutations?

A

if an organism cannot convert one particular compund to another. It lacks enzyme required for the next step

17
Q

explain the central dogma

A

transcription and translation etc.

18
Q

protein synthesis isnt always like central dogma …

A

because of virus. sometimes RNA and code and then go into a polypeptide.

19
Q

EXPLAIN initiation, elongation and termination.

A

The promoter, the coding aka the continuation, the release

20
Q

What editing sequence is removed and which on stays

A

Introns
Exon

21
Q

Transcription details

A

Promoter,RNA polymerase, mRNA, 5cap and poly tail

22
Q

explain translation

A

RNA to PROTEIN. relies on gentic code. also think about APE system when making a polypeptide

23
Q

tRNA

A

anticodon and amino acid attachment site

24
Q

tRNA synthase

A

amino acids charged with ATP. phosphates and bind to their matching tRNA which fuels peptide bond formation.

25
Q

A site, P site and E site

A

A site gets the ribosome then P site has the start codon and then E site has the release.

26
Q

The rest of the process relies on cellular structures of the endomembrane system.

A

LUMEN, vesicles, packaging etc. But post translation has …
phosphate groups, adding sugar, cleaving polypeptides etc.

27
Q

remember the 4 levels of protein structures.

A

primary
secondary
tertiary
Quatendary