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5. Metabolismo de la glucosa y lipidos > 5.1.5 Inhibidores de la dipeptidil peptidasa-4: SAXAGLIPTINA > Flashcards

5.1.5 Inhibidores de la dipeptidil peptidasa-4: SAXAGLIPTINA Flashcards

1
Q

Inhibidor de la DPP4

A

Saxagliptina

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2
Q

Quéprovoca la inhibición de DPP4

A

Aumenta la glp1 lo que auemnta la insulina, disminuye glucagón y el vaciamiento gástrico

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3
Q

Indicaciones terapeuticas

A

DMII y protección de hormonas incictinas endógenas potenciando sus acciones

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4
Q

Metabolito activo de la saxagliptina

A

5-hidroxisaxagliptina

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5
Q

Metabolismo de saxagliptina

A

Hepático por CYP450

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6
Q

Reacciones adversas de la saxagliptina

A

Infecciones urinarias, del tracto superior y cefalea

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5. Metabolismo de la glucosa y lipidos (15 decks)

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