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Neurology > Polyneuropathy > Flashcards

Polyneuropathy Flashcards

1
Q

Motor nerve neuropathy signs

A

LMN signs:
Weakness -> Distal > proximal
Muscle wasting
Hypotonia
Hyporeflexia
Downgoing plantars

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2
Q

Sensory nerve neuropathy signs

A

Reduced sensation
Paraesthesia
Pain
Sensory ataxia

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3
Q

Autonomic dysfunction

A

Postural hypotension
Abnormal sweating
Diarrhoea and constipation
Urinary retention

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4
Q

Causes of sensorimotor neuropathy

A

Diabetes
B12/folate deficiency
Alcohol
Hypothyroidism
Vasculitis
HSMN/Charcot-Marie-Tooth

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5
Q

Causes of motor neuropathy

A

CIDP (Chronic GBS)
GBS
Diabetic amyotrophy

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6
Q

Causes of sensory neuropathy

A

Paraneoplastic
Friederichs ataxia

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7
Q

Investigations of polyneuropathy

A

History + exam
Bloods -> B12, folate, U&E, LFTs, TFTs, ANA, ANCA, paraneoplastic antibodies
Neurophysiology -> EMG and nerve conduction studies
CT/PET CT for malignancy

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