L18: interactive lecture

Question 1

1. Which forms of lifespan have been increasing steadily over the last decades?

Answer 1

Average lifespan
Average healthspan
(not max lifespan or ess lifespan)

Question 2

Over the next 80 years, the Dependency Ratio
increases from 30 to 70.

Answer 2

Amount of retired people
per 100 working people

Question 3

How many CpG sites are measured in Horvath’s
clock algorithm?

Answer 3

353

Question 4

Overexpression of which enzyme increases the
Hayflick Limit?

Answer 4

telomerase

Question 5

Inactivity -> 1 -> 2 -> skeletal muscle atrophy
Inactivity -> blocks 3 -> increases 2 -> skeletal muscle atrophy

Answer 5

1 insulin resistance
2 anabolic resistance
3. satellite cells

Question 6

PGC-1a is an important protein in which
hallmark of ageing?

Answer 6

Mitochondrial
dysfunctioning

Question 7

An MRI can be used to study
1muscle mass
2intermuscular fat
3type 2-fibre size
4mito functioning

which are correct?

Answer 7

1,2,4

Question 8

Which three-letter abbreviation is used for
Preclinical cognitive decline?Preclinical cognitive decline

Answer 8

SCD (Subjective cognitive decline)

Question 9

Serotonin is formed out of the amino acid 1 while dopamine and noradrenaline are made from the amino acid 2

Answer 9

1 tryptophan
2 tyrosine

Question 10

Which dietary strategies could work against
osteoporosis?

1 Increasing citrus fruit intake
2 Increasing veg intake
3 Increasing dairy intake
4 Increasing vit D intake

Answer 10

all

Question 11

Urea is reabsorbed in the collecting tubule of
the kidney. The reabsorption of urea is
important for the functioning of a specific part
of the kidney. Please indicate the area of the kidney.

Answer 11

descending limb