vitamins nutrition Flashcards
Vitamin C is considered to be ANTI..
scurvy
What is the function of Vit C
-Co enzyme for hydroxylation reactions
(reducing agents )
-reduces Ferric to ferrous in Iron absorption
-Anti oxidant
what are the hydroxylation reactions that VIT C
participate in
-Hydroxylation of proline and lysine in collagen
synthesis.
-Bile acid formation
-corticosteroid synthesis in suprarenal gland
-Tyrosine catabolism and synthesis of
norepinephrine and epinephrine.
When does the vitamin C is concentrated in suprarenal gland
stress
vitamin C Deficiency causes
what can cause
scurvy
in diet poor or
excess in need (stress)
scurvy causes
Manifestations due to impaired
hydroxylation of proline and lysine in
collagen which leads to defective formation of
connective tissues, bone, cartilage and
dentine matrix
- Microcytic hypochromic anemia: may
occur due to extensive hemorrhage and
defective iron absorption.
Vitamin B1 functions :
Co enzyme TPP and has role in
1- oxidative decarboxylation of pyruvate
2- transketolase in HMP
Vitamin B1 deficiency causes :
Beri-beri (weakness);
Infantile beri beri: tachycardia , vomiting ,
convulsions,if not treated death
Wet beri beri (oedematous beri beri): CVS
manifestations as leg, trunk and face edema
due to heart failure .
Adult Dry beri beri ( neuritic beri beri):
CNS manifestations :muscle wasting ,
difficult walking, peripheral neuritis and finally
paralysis.
Wernicke-Korsakoff Syndrome :
Acute deficiency is seen in alcoholics
and called cerebral Beri beri
Wernicke-Korsakoff Syndrome causes paralysis of :
ocular muscles(nystagmus),.
Wernicke-Korsakoff manifestations:
encephalopathy, Ataxia, confusion,
Riboflavin (B2) charectarsitcs
composed of flavin ring attached to
D-Ribitol.
yellow colored
sensitive to light and high temperature,
2 active coenzymes are produced by Riboflavin B2 :
what are their function ?
FMN and FAD
both acting as
hydrogen carriers in enzymatic reactions
catalaysed by oxido-reductases
the importance of FMN and FAD are :
metabolism of carbohydrates, lipids, some
amino acids and in respiratory chain for
ATP synthesis
in general deficiency in B family Vitamin cause:
corneal vascularization
dermatitis
glossitis
Cheilosis
Anemia erythroid hypoplasia