Exam 2 drug doses

Question 1

Methohexital dose:
Induction:
Per rectum

Answer 1

o Induction: 1.5 mg/kg IV
o Per rectum: 20-30 mg/kg

Question 2

Thiopental dose:
Induction

Answer 2

o 4 mg/kg

Question 3

Propofol doses (WE USE 1%= 10 mg/mL):
o Induction:
o Pediatric induction:
o Elderly induction:
o Conscious sedation:
o Maintenance:
o Sub-hypnotic:

Answer 3

o Induction: 1.5-2.5 mg/kg
o Pediatric induction: 3 mg/kg
o Elderly induction: 1 mg/kg
o Conscious sedation: 25-100 mcg/kg/min (minimal amnesia & analgesia, low PONV)
o Maintenance: 100-300 mcg/kg/min
o Sub-hypnotic: 10-15 mg IV & then 10 mcg/kg/min

Question 4

Etomidate dose:
Induction dose:

Answer 4

o 0.3 mg/kg (no analgesia, must use opioid)

Question 5

• Ketamine doses:
  o Induction:
  o Maintenance:
  o Post-op:
  o Neuraxial:
  o CAD infusion cocktail:

Answer 5

o Induction: 0.5-1.5 mg/kg IV or 4-8mg IM
o Maintenance: 0.2-0.5 mg/kg
o Post-op: 1-2 mg/kg/hr (good for peds cardiac Sx)
o Neuraxial: 30mg epidural or 5-50 mg in 1L NS intrathecal
o CAD infusion cocktail: 0.5 mg/kg diazepam & 0.5 mg/kg ketamine then 15-30 mcg/kg/min ketamine infusion

Question 6

• Morphine doses:
  o Intra-op:
  o Post-op:

Answer 6

o Intra-op: 1-10 mg IV
o Post-op: 5-20 mg

Question 7

• Fentanyl doses:
  o Analgesia:
  o Induction:
  o Adjunct to gases:
  o Solo anesthesia infusion:
  o Intrathecal:
  o Transmucosal:
  o Transdermal:

Answer 7

o Analgesia: 1-2 mcg/kg IV
o Induction: 1.5-3 mcg/kg IV 5mins prior
o Adjunct to gases: 2-20 mcg/kg IV
o Solo anesthesia infusion: 50-150 mcg/kg IV
o Intrathecal: 25 mcg/kg
o Transmucosal: 5-20 mcg/kg
o Transdermal: 75-10 mcg

Question 8

• Sufentanil doses:
  o Analgesia:
  o Induction:
  o Intra-op:
  o Infusion:

Answer 8

o Analgesia: 0.1-0.4 mcg/kg
o Induction: 18.9 mcg/kg
o Intra-op: 0.3-1 mcg/kg (bolus or infusion)
o Infusion: 0.5-1 mcg/kg/hr

Question 9

• Alfentanil doses:
  o Induction (laryngoscopy):
  o Maintenance:
  o Induction alone:

Answer 9

o Induction (laryngoscopy): 15-30 mcg/kg
o Maintenance: 25-150 mcg/kg/hr (w/ gasses)
o Induction alone: 150-300 mcg/kg IV

Question 10

• Remifentanil doses:
  o Induction:
  o Maintenance:

Answer 10

o Induction: 0.5-1 mcg/kg IV q10mins
o Maintenance: 0.25-1 mcg/kg IV or 0.005-2 mcg/kg/min

Question 11

• Hydromorphone:
  o Intra-op:
  o Post-op:

Answer 11

o Intra-op: 1-4 mg
o Post-op: 1.5-4 mg

Question 12

• Codeine doses:
  o Cough suppressant:
  o Analgesia:

Answer 12

o Cough suppressant: 15 mg
o Analgesia: 60 mg

Question 13

• Pentazocine doses:
  o Chronic pain (IV, IM & PO):

Answer 13

• IV: 10-30 mg
• IM: 20-30 mg
• PO: 50 mg

Question 14

• Dezocine doses:
  o IM dose:

Answer 14

o IM dose: 10-15 mg IM

Question 15

• Naloxone doses:
  o IVP:
  o Infusion:
  o Epidural:
  o Shock:
  o Intra & post-op:

Answer 15

o IVP: 1-4 mcg/kg
o Infusion: 5 mcg/kg
o Epidural: 0.25 mcg/kg/hr
o Shock: >1 mg/kg
o Intra & post-op: 40-80 mcg

Question 16

• Nalmefene doses:
  o Dose:

Answer 16

o Dose: 15-25 mcg IV q2-5mins up to 1 mcg/kg

Question 17

• Gabapentin doses:
  o Pre-op:

Answer 17

o Pre-op: 300-1200 mg PO 1-2hrs before Sx

Question 18

• Ketorolac doses:
  o Regular dose:
  o Max dose:

Answer 18

o Regular dose: 15-30 mg q6 (1/2 in elderly)
o Max dose: 60-120 mg/day

Question 19

• Lidocaine doses:
  o IVP:
  o Infusion:

Answer 19

o IVP: 1-2 mg/kg IV over 2-4mins
o Infusion: 1-2 mg/kg/hr

Question 20

• Magnesium doses:
  o Pre-op:
  o Intra-op:

Answer 20

o Pre-op: 50mg/kg IV
o Intra-op: 8 mg/kg/hr

Question 21

• Decadron doses:
  o Regular dose:

Answer 21

o Regular dose: 8-10 mg

Question 22

• Ibuprofen doses:
  o Regular dose:
  o Max dose:

Answer 22

o Regular dose: 200-800 mg q6h
o Max dose: 3,200 mg/day