Endocrine Diseases Introduction

Question 1

What are some common Sx in endocrine diseases?

Answer 1

Tiredness
Fatigue
Lethargy
Weakness
Appetite changes
Thirst
Body size and shape changes
Skin changes: thinning, thickening, bruising, dry, greasy
Hair loss or excess
Menstruation changes
Altered childhood development
Problems with libido/potency

Question 2

What endocrine effect do tradition anti-psychotics (haloperidol, risperidone, chlorpromazine), Oestrogens, DA antagonist anti-emetics (metoclopramide, domperidone) have?

Answer 2

Increase prolactin –> galactorrhoea + oligo/amenorrhoea

Question 3

What endocrine effect does iodine, amiodarone and some immune modulators have?

Answer 3

Hyperthyroidism

Question 4

What endocrine effect does lithium and amiodarone have?

Answer 4

Hypothyroidism

Question 5

What endocrine effect can some diuretics induce?

Answer 5

Secondary aldosteronism

Question 6

What endocrine effect can ACE inhibitors have?

Answer 6

Hypoaldosteronism

Question 7

What drugs can mimic thyrotoxicosis or phaeochromocytoma?

Answer 7

Sympathomimetics
Amphetamines

Question 8

What endocrine effects can steroids cuase?

Answer 8

Cushing’s syndrome
Diabetes

Question 9

What can anabolic steroids (androgens) cause?

Answer 9

Suppression of the gonadal axis

Question 10

What endocrine effect can excess vitamin D preparations cause?

Answer 10

Hypercalcaemia