Motion sickness

Question 1

Diphenhydramine

Answer 1

Benadryl

Question 2

dimenhydrinate

Answer 2

Dramamine

Question 3

Meclizine

Answer 3

Dramamine All Day Less Drowsy

Question 4

Scopolamine

Answer 4

Transderm Scop

Question 5

Metoclopramide and the SHT-3receptor antagonists (e.g., ondansetron) in motion sickness

Answer 5

are generally not effective for motion sickness.

Question 6

Only one antiemetic works well for motion sickness. What is it?

Answer 6

PROMETHAZINE
is prescription only and should not be used in children due to the risk of respiratory depression. All promethazine products carry a boxed warning to avoid use in children less than 2 years old and strongly caution against use in children age 2 and older

Question 7

Scopolamine patch frequency

Answer 7

one patch every 3 days PRN

Question 8

CI of scopolamine patch

Answer 8

Hypersensitivity to belladonna alkaloids, closed-angle glaucoma

Question 9

SE of scopolamine

Answer 9

Dry mouth, CNS effects [drowsiness, dizziness, confusion (can be significant in elderly, frail), hallucinations (rare)], stinging of the eyes and pupil dilation (if eyes are touched after handling), risk of increased IOP,tachycardia (rare)

Question 10

Should we remove Scopolamine patch before MRI ?

Answer 10

Yes

Question 11

can you use scopolamine in children?

Answer 11

No do not use in children.

Question 12

Counsel on scopolamine patch for N/V due to motion sickness or anaesthesia/surgery

Answer 12

• Apply at least 4 hours before needed or the night before surgery
• Press firmly to skin behind ear for 30 seconds
• Try to avoid placing the patch over hair, or when the patch is removed, the hair may be removed, too
  -Lasts 3 days; if continued treatment needed, remove the first patch and place a new patch behind the other ear.
  -Wash hands after applying
  -Do not drive: high level of sedation, dizziness,confusion - these anticholinergic side effects are worse, and not well-tolerated, in elderly patients (avoid use when possible)

Question 13

scopolamine uses

Answer 13

motion sickness
pre-op C section

Question 14

Dimenhydrinate (Dramamine) class and uses

Answer 14

First Generation Antihistamine H1
Motion sickness
N/V

Question 15

Warning with Dramamine

Answer 15

CNS DEPRESSION (may impair physical or mental abilities, caution in elderly), worsening of BPH symptoms, INCREASE IOP (GLAUCOMA)

Question 16

SE of dramamine

Answer 16

Dizziness
Drowsiness
Dry mouth
Blurry vision

Question 17

Difference between Dramamine original formula and dramamine all day less drowsy

Answer 17

There are various OTC formulations of Dramamine with different ingredients.
Dramamine Original Formula contains only dimenhydrinate.

Dramamine All Day Less Drowsy contains only meclizine.

Question 18

What is Meclizine

Answer 18

Dramamine All Day LessDrowsy

Meclizine is a first-generation antihistamine (non-selective H1 antagonist). It also has central anticholinergic actions. [5] The blocking actions on these receptors give meclizine its antiemetic and antivertigo properties.

Question 19

Warning, SE and common use of Meclizine

Answer 19

WARNINGS
CNS depression (may impair physical or mental abilities, caution in elderly), worsening of BPH symptoms, i IOP (glaucoma)

SIDE EFFECTS
Sedation, dry mouth, dry/blurry vision, tachycardia

NOTES
Meclizine is commonly used for vertigo; it was previously branded as Antivert

Question 20

All antihistamines have anticholinergic effects similar to scopolamine. Oral agents must be taken _____ minutes before effect is needed

Answer 20

30-60 min

Question 21

Scopolamine has this major set of side effects and can cause ___ if you get it in your eye

Answer 21

Anticholinergic! Stinging of the eyes and pupil DILATION