Retinoblastoma Flashcards
1
Q
Genetic pattern
A
Autosomal dominant
2
Q
Pathophysiology
A
Loss of function of the Rb tumour suppressor gene on chromosome 13
3
Q
Epidemiology
A
Picked up by 18 months
10 percent hereditary
4
Q
Symptoms/signs
A
Absence of red light reflex
Strabismus (misaligned eyes)
White pupil (leukocoria)
5
Q
Management
A
External beam radiation therapy
Chemotherapy
Photocoagulation
6
Q
Prognosis
A
90 percent survive to adulthood
v good prognosis
