Pralidoxime Chloride

Question 1

Pralidoxime Chloride Class

Answer 1

Cholinesterase Reactivator, Antidote

Question 2

Pralidoxime Chloride Action

Answer 2

Reactivates cholinesterase in cases of organophosphate poisoning, causing a decrease in acetylcholine and its parasympathetic effects; deactivates certain chemical organophosphates or nerve agents through a direct chemical reaction

Question 3

Pralidoxime Chloride Indications

Answer 3

Organophosphate and nerve agent poisoning; used in conjunction with atropine

Question 4

Pralidoxime Chloride Contraindications

Answer 4

Inorganic Phosphate Poisoning

Question 5

Pralidoxime Chloride Side Effects

Answer 5

Tachycardia, Hypertension, Blurred Vision, headache, nausea, Muscle weakness

Question 6

Pralidoxime Chloride Adult Dose IV

Answer 6

1-2 g in 250/500 mL NaCl over 30 min

Question 7

Pralidoxime Chloride Adult dose IM/SC:

Answer 7

1-2 g

Question 8

Pralidoxime Chloride Pedi dose IV:

Answer 8

20-40 mg/kg in 250/500 mL NaCL over 30 min

Question 9

Pralidoxime Chloride Pedi dose IM/SC:

Answer 9

1-2 mg/kg

Question 10

Pralidoxime Chloride Onset

Answer 10

10-20 min

Question 11

Pralidoxime Chloride Duration

Answer 11

1 hr