Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

random > liver > Flashcards

liver Flashcards

1
Q

what LFT ratio is good for alcholic hepatitis

A

AST:ALT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what AST:ALT ratio is suggestive of alcoholi hapetitis

A

> 3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

treatment for acute episode of alcoholi hepatitis

A

steroid e.g prednisolone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

when are mallory bodies seen

A

alcoholic hepatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

most common cause of liver disease in the developed world

A

non-alcoholic fatty liver disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Non-alcoholic steatohepatitis is patholigically identicle to…?

A

alcoholic liver disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

key mechanism for steatosis in NASH is through …?

A

insulin resistance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

associated factors of NAFLD

A

obestity
T2DM
Hyperlipideamia
sudden weight loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what is seen on ultrasound in NAFLD

A

increase echognicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

diagnosis of NAFLD

A

enhance liver fibrsis (ELF test) - blood test

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

management of NAFLD

A

weight loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

diagnostic test for liver cirrhosis

A

transient elastography

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

how is hep B spread

A

exposure to infected blood or body fluids, including vertical transmission from mother to child.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

symptoms of hep b

A

fever jaundice deranged LFT’S

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

complications of hep B

A

chronic hepatitis
hepatocellular carcinoma
GN
polyarteritis nodosum
cryoglobinaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what hepatitis’ can become chronic

A

B and C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what Ig is hepatitis B

A

IgM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

how is hep E spread

A

faceal oral route

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

if someone has severe heaptitis in preganncy what shoud you thinl

A

hep E

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

who gets Hep D

A

those already infected with Hep B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

how is hep C spread

A

via blood-to -blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

most at risk of Hep c

A

iVDU

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

can you breast feed with hep c

A

yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

is there a vaccine for hep C

A

NO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

features of hep C

A

fever
arthralgia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

diagnostic test for Hep C

A

HCV RNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

treatment of hepatitis B

A

pegylated interferon alpha

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

what is a common feature of autoimmune hepatitis that does not involve liver symptoms

A

amenorrhoea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

antibodies seen in autoimmune heaptitis

A

ANA
ASMA and
LMK1

30
Q

what autoimmune hepatitis is only seen in children and what antibody is assoc with this

A

type 2
LMK1

31
Q

what Ig is raised in autoimmune hepatitis

A

IgG

32
Q

piecemeal necrosis on liver biospy indicates…?

A

autoimmune heaptitis

33
Q

treatment of autoimmune hepatitis

A

steroids

34
Q

who gets PBC

A

middle ages women

35
Q

does PBC involve the intra or extra hepatic ducts

A

intra

36
Q

what is the classic presentation of PBC

A

itching in a middle aged woman

37
Q

end result of PBC

A

liver cirrhosisi

38
Q

what conditions are assoc with PBC

A

sjogrens
RA
systemic sclerosi s
thyroid disease

39
Q

what would be seen on immunolgy in PBC

A

AMA M2 subtype
raised IgM

40
Q

what test must be doen before diagnosis of PBC and why

A

a RUQ USS or MRCP to exclude biliary obstruction

41
Q

management of PBC

A

urseodeoxycolic acid

42
Q

what can be given for itch in PBC

A

cholestyramine

43
Q

what vitamins need to be supplemented in PBC

A

fat soluble vitamins eg ADEK

44
Q

PBC increases risk of what cancer

A

hepatocellular carcinoma

45
Q

most common chrons symptom in children versus adults

A

children - abdo pian
adults - diarrhoea

46
Q

what is someone injected with in the heaptitis B Vaccine

A

HBsAg- surface antigen

47
Q

What is the most specific blood result for progressing to cirrhosis in individuals with chronic liver disease

A

thrombocytopenia

48
Q

cardiac effect of carcinoid tumours

A

affect right side of the heart
pulmonary stenosis and tricupsid regurgitation

49
Q

complications of enteral feeding

A

diarrhoea
aspiration
hyperglycaemia and
refeeding

50
Q

what x-ray is doen for upper abdo pain

A

erect CXR

51
Q

what artery is most likely bleeding in a duodenal ulcer

A

gsatroduodenal ulcer

52
Q

triad of symptoms in budd chairi

A

abdo pain
ascites
render heaptomegaly

53
Q

painless jaundice with palpable gallbladder

A

cancer - biliary or pancreatic

54
Q

inheritance pattern in haemochromatosis

A

auto recessive

55
Q

what stain is used to identify iron on liver

A

perls prussian blue

56
Q

gene involevd in haemochromatosisi

A

HFE

57
Q

treatment of haemochromatosisi

A

venesection

58
Q

inheritance pattern of wilsons

A

auto recessive

59
Q

where does copper accummulate in wilsons

A

liver and basal ganglia

60
Q

what test is used to identify wilsons and what would result be

A

decrease serum ceruloplasmin

61
Q

what happens to free an bound serum copper in wilsons

A

free is increased
bound is decreased as most is bound to ceruloplasmin

62
Q

Tx of wilsons

A

copper chelating drugs e.g. penacilliamine

63
Q

gene implicated in wilsons

A

ATP7B

64
Q

inheritance of alpha 1

A

auto recessive

65
Q

gene implicated in alpha 1

A

A1AT

66
Q

symptoms of diverticular disease

A

PR bleeding
abdo pain
altered bowel habit
bloating

67
Q

what tests are used to minotr haemochromatosis

A

transferrinn and derum ferritin

68
Q

a SAAG level of what indicates a portl hypertension cause in ascites

A

> 11g/L

69
Q

in patients with ascites when shoudl prophylactic bacterial peritonitis antibitotics be given and what type

A

patients who have had an episode of SBP
patients with fluid protein <15 g/l and either Child-Pugh score of at least 9 or hepatorenal syndrome

oral ciprofloxacin

70
Q

first line antibody testing in coeliac

A

IgA and IgA TTG

71
Q

what Hb level warrants blood tranfusion

A

<70g/l or <80 if IHD

random (19 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions