LAS 4 - ANTIEPILECTICS

Question 1

WHAT ARE THE 3 HYDANTOINS?

Answer 1

PHENYTOIN, MEPHENYTOIN, ETHOTOIN

Question 2

CONSIDER AS IMIDAZOLINE-2,4-DIONE HETEROCYCLIC SYSTEM

Answer 2

HYDANTOINS

Question 3

WHAT IS THE IMPACT OF PHENYL SUBSTITUENT IN P5 IN HYDANTOINS?

Answer 3

ANTI-EPILEPTIC ACTIVITY

Question 4

WHAT IS THE IMPACT OF ALKYL SUBSTITUENT IN P5 IN HYDANTOINS?

Answer 4

SEDATION ACTIVITY

Question 5

WHAT IS THE MOA OF PHENYTOIN?

Answer 5

BLOCKAGE OF CA+ AND NA+( NON-SELECTIVE)

Question 6

HAS THE AE OF HIRUSTISM, GUM HYPERTROPHY…

Answer 6

PHENYTOIN (HYDANTOINS)

Question 7

-DIONE
TRIMETHADIONE, PARAMETHADIONE ARE…

Answer 7

OXAZOLISINEDIONES

Question 8

-IMIDE
PHENSUMIDE, METHSUXMIDE, AND ETHOSUXIMIDE ARE…

Answer 8

SUCCINIMIDES

Question 9

FIRST-LINE-DRUG FOR GENERALIZED ABSENCE SEIZURE

Answer 9

ETHOXSUXIMIDE

Question 10

FIRST-LINE-DRUG FOR STATUS EPILEPTICUS

Answer 10

DIAZEPAM

Question 11

KNOWN FOR ITS BROAD SPECTRUM ACTIVITY

Answer 11

VALPROIC ACID

Question 12

TRIMETHADIONE IS?

Answer 12

PROTOTYPE OF OXAZOLIDINEDIONES

Question 13

IS A BRANCHED-CHAIN (SATURATED) FATTY ACID THAT COMPRISES A PROPYL SUBSTUTUENT ON A PENTANOIC ACID STEM

Answer 13

VALPROIC ACID

Question 14

WHAT SEIZURES DOES VALPROIC ACID ARE EFFECTIVE?

Answer 14

ABSENCE
MYOCLONIC PARTIAL
TONIC-CLONIC SEIZURES

Question 15

LAMOTRIGINE, GABAPENTIN, VIGABATRIN, AND FUNCTIONALIZED AMINO ACID ARE…

Answer 15

NOVEL ANTIEPILEPTICS