Thyroid Disorders Flashcards

1
Q

True or false: Thyroid disorders are more prominent in men than women

A

False. More prominent in women

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2
Q

Normal TSH range

A

0.5 - 4.7 mlU/L

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3
Q

Parameters of TSH in hypothyroidism

A

TSH > 4.7

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4
Q

Parameters of TSH in hyperthyroidism

A

TSH < 0.5

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5
Q

True or false: No antithyroid drug is useful in treating thyroiditis

A

True

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6
Q

Excess ingestion of what can interfere with immunoassays leading to falsely elevated TT4, FT4 and TT3, and falsely low TSH levels?

A

Biotin

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7
Q

What is Plummer’s disease and the first line treatment?

A

Hyperthyroidism characterized by multinodular goiters. Surgery is treatment of choice

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8
Q

Thyroid storm is often seen in what form of hyperthyroidism?

A

Graves’ Disease

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9
Q

What are the two main goals of hyperthyroidism treatment?

A
  • Relieve signs and symptoms
  • Become euthyroid
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10
Q

What is the Wolff-Chaikoff effect?

A

Transient inhibition of thyroid hormone biosynthesis following the administration of iodides

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11
Q

Which two beta blockers partially block peripheral conversion of T4 to T3?

A

.Propranolol
.Nadolol

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12
Q

Which is the preferred beta blocker in thyroid storm?

A

IV esmolol

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13
Q

What is the most common cause of spontaneous hypothyroidism?

A

Hashimoto’s disease

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14
Q

What is the term for acute decompensated hypothyroidism?

A

Myxedema coma

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15
Q

Elevated TSH with normal FT4 is a sign of what?

A

Subclinical hypothyroidism

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16
Q

Replacement dose of levothyroxine

A

1.6 mcg/kg/day (IBW)

17
Q

Levothyroxine starting dose in relatively healthy elderly patients

A

50 mcg/day

18
Q

Levothyroxine starting dose in patients with known CAD

A

12.5-25 mcg/day

19
Q

True or false: Amiodarone can block conversion of T4->T3

A

True

20
Q

Liotrix contains T4 and T3 in what ratio?

A

4:1

21
Q

What dose increase in suggested pregnancy?

A

~50% increase