2.4 Heart Flashcards

1
Q

phase 0 of the CAP

A

Na

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2
Q

phase 2 of the CAP

A

Ca open

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3
Q

phase 3 of the CAP

A

K open
Ca close

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4
Q

phase 4 of the CAP

A

resting/pacemaker

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5
Q

QT is ___-dependent and must be adjusted at HR > ___

A

rate
60

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6
Q

delayed after depolarization due to what?

A

Ca influx

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7
Q

class ___ and III work on phase 3 of the CAP

A

Ia

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8
Q

binding strength of class I (high to low)

A

CAB

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9
Q

dissociation speed of class I (high to low)

A

BAC

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10
Q

class I_ can cause QT prolongation

A

Ia

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11
Q

class I_ can cause anticholinergic symptoms

A

Ia

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12
Q

class I_ can cause altered taste

A

Ic

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13
Q

NSAIDs reduce effectiveness of what class?

A

beta blockers

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14
Q

CCBs ___ the plateau phase

A

shorten (phase 2)
(and decrease DAD)

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15
Q

di vs non-di CCBs (side effects)

A

reflex tachycardia vs bradycardia/AV block

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16
Q

EF = ___/___

A

SV/EDV

17
Q

inotropy = ___

A

contraction

18
Q

digoxin exhibits ___-control

A

rate-control

19
Q

digoxin effect is increased with ___ K

A

decreased

20
Q

increases gag reflex

A

digoxin

21
Q

avoid dental light (2)

A

amiodarone
digoxin

22
Q

levosimendan MOA

A

Ca sensitizer and vasodilation (Katp activation)

23
Q

double product

A

HR x systolic BP

24
Q

MVO2 = what?

A

myocardial oxygen demand

25
Q

improves angina without changing HR or BP

A

ranolazine (inhibits Na channel)
QT prolongation adverse reaction

26
Q

increases O2 supply and decreases O2 demand

A

CCBs

27
Q

causes xerostomia (2)

A

class Ia
ranolazine