MHC (Exam 1)

Question 1

What are the only thing T cells can recognize?

Answer 1

short linear peptides

Question 2

A T cell can only recognize its specific antigen. What two things need to be correct for it to recognize and respond?

Answer 2

1. correct MHC molecule
2. correct peptide

Question 3

Term for the fact that T cell can only recognize antigen when it has the correct MHC molecule and peptide.

Answer 3

MHC restriction

Question 4

(T/F) T cells can recognize and respond to antigen with MHC interaction.

Answer 4

False

Question 5

What are APCs?

Answer 5

antigen-presenting cells

Question 6

What are the 3 types of professional antigen-presenting cells?

Answer 6

1. dendritic cells
2. macrophages
3. B cells

Question 7

Dendritic cells act as APCs when they take up antigen and express ________ which is the second signal for an adaptive immune response to occur.

Answer 7

costimulatory molecule (B7)

Question 8

Term for process of APCs to help T cells become activated.

Answer 8

co-stimulation

Question 9

_______ is often added with vaccines to allow for a greater response of protection and activation of T cells.

Answer 9

adjuvant