Drug Induced Rashes Flashcards

1
Q

List some types of drug induced rashes

A

morbilliform
hives
photosensitive reactions
SJS/TEN
toxic epid necrolysis

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2
Q

Describe morbilliform

A

eruptions
measles like (most common)
maculopapular (pimple)
they look like hives

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3
Q

What is the most common causes of morbilliform for adults and for kids?

A

Adults –> from drugs
Kids –> from viral infections

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4
Q

What are the percentages of people who will get a rash from meds?

A

less than 2%

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5
Q

How common are morbilliforme?

A

of the few who get rashes from meds about 95% of these will get morbilliform

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6
Q

What is the timeline for morbilliform?

A

appears ~1-2 wks after starting drug and can be up to 1 wk after stopping
very rare for a drug that you have been taking for several months or years

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7
Q

Where is the most common place for morbilliform?

A

usually found on the trunk and spreads to the limbs/neck

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8
Q

What is the timeline for morbilliform after stopping the drug?

A

It should improve by 48 hrs and clear after 1 wk

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9
Q

When to refer skin rashes?

A

if there is pus or blisters refer and stop the drug!

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10
Q

What is another name of urticarial rash?

A

hives

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11
Q

Describe the phototoxic reaction

A

fast onset
looks like a sunburn

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12
Q

When will phototoxic reactions clear up?

A

Once the drug is discontinued has cleared from the body –> worsening sun reactions

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13
Q

Describe photoallergic reactions

A

rare
body saying its allergic + UV radiation –> eczema like tend to be chronic

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14
Q

Are photoallergic reactions more common with oral or topical medication?

A

Topical meds

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15
Q

What is SJS?

A

Stevens-Johnson syndrome

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16
Q

List some symptoms of SJS

A

skin pain - first differential
flu like symp
rash only after first two symptoms
blisters and open wounds
mucous membrane involved

17
Q

What is the timeline for SJS?

A

starts within 8 wks
usually in 4-30 days

18
Q

How serious is SJS?

A

it is life threatening
don’t take a chance go to MD