Blood Transfusion- indications

Question 1

what are indications for red cell transfusion?

Answer 1

-major bleed
-Symptomatic anaemic Hb<70g/L
(<80g/L if cardiac disease)

Question 2

what are indications for platelet transfusion?

Answer 2

-prophylaxis in patients with bone marrow failure or very low platelet count

-treatment of bleeding in thrombocytopenic patients (low platelets)

-prophylaxis prior to surgery/ procedure in thrombocytopenic patients

Question 3

what are indications for fresh frozen plasma?

Answer 3

-treatment of bleeding patient with coagulopathy (PT> 1.5)
-Prior to surgery or procedure with coagulopathy (PT ratio >1.5)
-managmenet of massive haemorrhage
-transfuse in early trauma

Question 4

how are red cells stored?

Answer 4

35 days at 4 degrees

Question 5

how is FFP stored?

Answer 5

3 years at -30 degrees

Question 6

how are platelets stored?

Answer 6

22 degrees for 7 days with agitation

Question 7

what does fresh frozen plasma contain?

Answer 7

-clotting factors
-albumin
-immunoglobin

Question 8

what does cryoprecipate contain?

Answer 8

-Factor VIII
-Fibrinogen

Question 9

advantage of cryoprecipitate?

Answer 9

allows large concentration of factor VIII to be administered in small volume