Chapter 25: Antidysrhythmic Drugs

Question 1

its only use is for ventricular dysrhythmias

Answer 1

lidocaine

Question 2

very short half-life of less than 10 seconds

Answer 2

adenosine

Question 3

used for life-threatening dysrhythmias (2)

Answer 3

flecainide, propafenone

Question 4

will cause a brief episode of asystole after administered

Answer 4

adenosine

Question 5

disturbances of cardiac rhythm are result of abnormally functioning ____________

Answer 5

cardiac cells

Question 6

this classification system is based on the electrophysiological effects of drugs on the action potential of the heart

Answer 6

Vaughn Williams Classification System

Question 7

long-term use leads to corneal microdeposits

Answer 7

amiodarone

Question 8

can cause a systemic lupus erythematous-like syndrome (contraindicated with SLE)

Answer 8

procainamide

Question 9

preferentially blocks the beta1-adrenergic receptors that are located primarily in the heart

Answer 9

cardioselective beta blockers

Question 10

can cause pulmonary toxicity and hepatotoxicity

Answer 10

amiodarone

Question 11

significant reactions with warfarin and digoxin

Answer 11

amiodarone

Question 12

requires special training to administer

Answer 12

dofetilide

Question 13

intrinsic rate of 40-60 bpm

Answer 13

AV node

Question 14

dosage based on body weight

Answer 14

ibutilide

Question 15

only administered as fast IV push

Answer 15

adenosine

Question 16

requires continuous cardiac monitoring for first 3 days of use

Answer 16

dofetilide

Question 17

slows conduction through the AV node

Answer 17

adenosine

Question 18

used for atrial and ventricular tachydysrhythmias caused by digitalis toxicity or long QT syndrome

Answer 18

phenytoin

Question 19

intrinsic rate of <40 bpm

Answer 19

Purkinje fibers

Question 20

intrinsic rate of 60-100 bpm

Answer 20

SA node

Question 21

rapid conversion for Afib and Aflutter to normal sinus rhythm

Answer 21

ibutilide

Question 22

natural pacemaker of the heart

Answer 22

SA node

Question 23

can cause cinchonism: tinnitus, blurring vision, GI upset

Answer 23

quinidine

Question 24

contraindicated in heart blocks

Answer 24

beta blockers (II)

Question 25

indicated for supra and ventricular dysrhythmias

Answer 25

beta blockers (II)

Question 26

risk for Torsades de Pointes (2)

Answer 26

quinidine (black box warning)
dofetilide

Question 27

all antidysrhythmic drugs can result in this abnormality

Answer 27

QT prolongation

Question 28

blocks beta1-adrenergic in heart and beta2-adrenergic receptors in lungs and can exacerbate pre-existing asthma or COPD

Answer 28

noncardioselective beta blockers

Question 29

black box warning for increased mortality

Answer 29

quinidine

Question 30

converts paroxysmal supraventricular tachycardia (PSVT) to normal sinus rhythm (NSR)

Answer 30

adenosine

Question 31

can result in ventricular dysrhythmias

Answer 31

ibutilide

Question 32

ACLS drug of choice for ventricular dysrhythmias

Answer 32

amiodarone

Question 33

two most reported side effects of propafenone

Answer 33

dizziness, metallic taste