lecture 22: population genetics 2, natural selection, and adaptation

Question 1

consanguinity

Answer 1

property of being descended from the same ancestor as another person

Question 2

why is inbreeding genetically bad

Answer 2

Question 3

identity by descent

Answer 3

inbreeding increases the percent homozygous because offspring can inherit two identical copies of an allele from the same ancestor

Question 4

inbreeding coefficient

Answer 4

the probability that a child born to related parents will be IBD at any locus

Question 5

calculating inbreeding coefficient

Answer 5

Question 6

malaria

Answer 6

Question 7

sickle cell resistance to malaria

Answer 7

Question 7

no selection

Answer 7

new allele under neutral evolution (no selection) rises and falls in prevalence by chance

Question 8

positive selection

Answer 8

new allele under positive selection rises rapid

Question 9

balancing selection

Answer 9

new allele under balancing selection rises rapidly in prevalence in the population up to an equilibrium point

Question 10

negative selection

Answer 10

new alleles under negative selection will get rapidly weeded out of the population

Question 11

how did we find genes

Answer 11

Question 12

human and chimp genomes

Answer 12

Question 13

why is purifying selection important

Answer 13

Question 14

how to detect positive selection

Answer 14