Sensitivity and Specificity Testing

Question 1

What is known as the true-positive rate?

Answer 1

Sensitivity

Question 2

What is known as the proportion of people with the disease who test positive?

Answer 2

True-positive AKA sensitivity

Question 3

Equation of Sensitivity

Answer 3

TPV/TD

Question 4

What is known as the true-negative rate?

Answer 4

Specificity

Question 5

What is known as the proportion of people testing negative who do not have the disease?

Answer 5

True-negative AKA specificity

Question 6

Equation of specificity

Answer 6

TNV/TND

Question 7

What is a downside of a highly sensitive test?

Answer 7

A higher rate of false positives

Question 8

What is an example of a high sensitivity and low specificity test?

Answer 8

Mammogram - depends on tumor size and patient age

Question 9

What is the downside of a test with high specificity?

Answer 9

A high false negative rate

Question 10

What is an example of a test with high specificity?

Answer 10

Nitrate dipstick used for UTI’s

Question 11

What is the positive predictive value (PPV)?

Answer 11

Probability of patients testing positive who actually have the disease

Question 12

Equation for PPV

Answer 12

TPV/TP

Question 13

What are PPV influenced by?

Answer 13

How common the disease is

Question 14

What is the negative predictive value (NPV)?

Answer 14

Probability of patients testing negative who truly don’t have the disease

Question 15

Equation for NPV

Answer 15

TNV/TN

Question 16

What is the accuracy (ACC) of a test?

Answer 16

Proportion of all tests in a study having a correct result

Question 17

Equation for ACC

Answer 17

(TPV + TNV) / TOT