Pharm Flashcards

1
Q

Mode of action of Spironolactone?

A

increases sodium and water excretion by competitively binding to aldosterone receptors in the distal tubules of the kidney

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2
Q

What is the mechanism of action of alendronic acid?

A

Inhibits osteoclastic activity to decrease bone resorption, which reduces bone turnover and improves bone mass

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3
Q

What is the mechanism of action of rivaroxaban?

A

DOAC

Directly inhibits activated clotting factor X to prevent conversion of prothrombin to thrombin

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4
Q

What are the common side effects of ACEi?

A
  • Cough. Seen in 15% of pts. Due to increased bradykinin
  • Angioedema
  • Hyperkalaemia
  • 1st dose hypotension
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5
Q

TB medication that can cause red urine.

A

Rifampicin

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6
Q

TB medication that can cause peripheral neuropathy

A

Isoniazid

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7
Q

TB medication that can cause optic neuritis

A

Ethambutol

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8
Q

TB medication that can cause hyperuricaemia (gout)

A

Pyrazinamide

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9
Q

What kind of drug is diclofenac?

A

NSAID

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10
Q

What kind of drug is Ticagrelor and what is its mechanism of action?

A

Antiplatelet medication
P2Y12 receptor antagonist

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11
Q

What is the first line medication used for rheumatoid arthritis?

A

DMARD
Methotrexate, Sulfasalazine, Rituximab…

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