Biological membranes Flashcards
Function of Glycoproteins
branching carbohydrate portion of a protein which acts as a recognition site for chemicals
role in cell adhesion and act as receptors for chemical signals
Function of Glycolipids
acts as a recognition site
antigens
Function of Cholesterol
stability/flexibility of protein
positioned between phospholipids
What is an extrinsic protein
a protein partly embedded into the bilayer e.g glycoproteins or glycolipids
What is an intrinsic protein
a protein embedded all the way through the bilayer e.g. channel or carrier proteins
Channel proteins
provide a hydrophilic pathway for passive movement of polar molecules or ions down a conc gradient
Carrier Protein
important role in both passive transport and active transport
the carrier protein changes to allow molecules to pass through
How does the temp affect the membrane
Increased temp gives the phospholipids more energy and will move more, making it more fluid, increasing permeability
very high temps causes the membrane to break down completely and intrinsic proteins will denature
Diffusion:
Definition
Factors that affect it
diffusion is the net movement of particles from an area of higher conc to an area of lower conc
temp - the higher the temp, the high the rate of diffusion, too high = denature
conc difference - the greater difference between the 2 regions, the faster diffusion is
in membranes:
surface area
thickness of membrane
Facilitated diffusions
diffusion using channel proteins or carrier proteins
NO ENERGY
DOWN A CONC GRADIENT
Active transport
net movement of molecules from an area of low conc to an area of high conc using energy
How do carrier proteins allow molecule through via active transport?
1 - molecule being transported binds to the receptor in the carrier protein on the outside of the cell
2 - on the inside of the cell ATP binds to the carrier protein where its hydrolysed into ADP and Pi
3 - Binding the Pi to the carrier protein causes it to change shape opening up into the cell
4 - molecule is released into the cell
5 - Pi is released from the carrier protein and recombines with ADP to ATP
6 - the carrier protein returns to its original shape
Osmosis
net movement of water molecules across a partially permeable membrane (passive)
what is water potential?
if a cell has lower WP then water will move into the cell
pure water is 0kPa
osmosis in animal cells
hypotonic - lower WP (in cell), water enters, cell bursts (cytolysis) (turgid in plants)
hypertonic - higher WP (in cell), water leaves, cell shrivels (crenation) (plasmolysis in plants)