periodontal microbiology Flashcards
1
Q
Biofilm development stages
A
- adhesion
- colonisation
- accumulation
- complex community
- dispersal
2
Q
P Gingivalis virulence factors
A
- host cell tissue adherence and invasion
- elaboration of proteases
- endotoxin
- capsular polysaccharide
- tissue toxic metabolic by-products e.g. ammonia
3
Q
how does p gingival manipulate host defences?
A
biofilm
ginigpains
induction of tissue destruction
subversion
4
Q
How gingipains manipulate host defences
A
- degradation of innate receptors
- degradation of cytokines
5
Q
Periodontal disease systemic implications
A
- increased risk of cardiovascular disease
- suggested increased risk of rheumatoid arthritis
- up to 6 fold increased risk of diabetes
6
Q
Periodontal disease systemic implications
A
- increased risk of cardiovascular disease
- suggested increased risk of rheumatoid arthritis
- up to 6 fold increased risk of diabetes
7
Q
important microbes in gingivitis
A
actinomyces
prevotella intermedia
bacteroides
fusobacterium nucleatum
8
Q
periodontitis microbes
A
- P. gingival
- T. forsythia
- T. denticola
- p. intermedia
9
Q
P gingival features
A
gram negative bacteria
non-motile rod
strict anaerobe
black pigmentation
10
Q
Periodontal disease - systemic implications
A
increased risk of cardiovascular disease
increased risk of diabetes up to 6 fold
suggested increased risk of rheumatoid arthritis
