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y3 summary > obs > Flashcards

obs Flashcards

1
Q

cancers worsened by oestrogen

A

cervical and breast

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2
Q

cancers worsened by progesterone

A

endometrial and ovarian

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3
Q

what antibody can pass through placenta

A

igG

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4
Q

ACEi/ARB effect in pregnancy

A

renal hypoplasia

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5
Q

androgen effect in pregnancy

A

virilisation of female foetus (genital ambiguity)

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6
Q

effect of anti-epileptics (not all of them)

A

cardiac, facial lumb neural tube defects

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7
Q

effect of lithium

A

CVS defects

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8
Q

effect of methotrexate

A

limb and facial defects

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9
Q

warfarin effect

A

limb and facial defects

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10
Q

why should you avoid amiodarone during breastfeeding

A

neonatal hypothyroidism

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11
Q

why do you REALLY REALLY NEED TO GIVE FOLATE with methotrexate always regardless of pregnancy

A

methotrexate is a folate antagonist

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12
Q

what is the consequence of not having folic acid during 1st trimester (up till 12w) pregnancy

A

baby fucked
microcephaly and neural tube defects (spina bifida)

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13
Q

what people require 5mg folic acid instead of 400ug

A

previous NTD
taking antiepileptics
coeliac
diabetes
thalassaemia trait
obesity af

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14
Q

Tx pregnant HTN

A

labetolol

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15
Q

N+v in preggers

A

cyclizine

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16
Q

UTI in 1st 2nd tri

A

nitrofurantoin

17
Q

UTI 3rd tri

A

tirmethoprim

18
Q

pain in pregnancy Tx

A

paracetamol NOT NSAIDs

(because nsaids inhibit prostaglandins and hence inc mother BP - as prostaglandins work as a vasodilator and lowers BP)

19
Q

DVT / PE in pregnancy

A

anticoag with LMWH (monitored with anti-Xa assay) as warfarin causes facial/limb defects

20
Q

baby head hits cervix

A

oxytocin release which promotes contractions - ferguson relfex

21
Q

progesterone in labour

A

Prevents!!! dec contractions

22
Q

oestrogen in labour

A

OPENS - inc contraction, promotes prostaglandin production

23
Q

first stage

A

onset of true labour to 10cm dilation

y3 summary (7 decks)

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