Congenital and Acquired Immunodeficiencies

Question 1

What is the name of the cancer of the epithelium?

Answer 1

carcinoma

Question 2

What is the name of the cancer of the connective tissue?

Answer 2

sarcoma

Question 3

What is the name of the cancer of the lymphoid system?

Answer 3

lymphoma

Question 4

What is the name of the cancer of the blood?

Answer 4

leukemia

Question 5

What are oncogenes?

Answer 5

Gene sequences that encourage cancer growth and proliferation

Question 6

What are tumor suppressor genes?

Answer 6

Genes that discourage/inhibit cell growth and proliferation

Question 7

What is immunosurveillance?

Answer 7

The ability of the immune cells to detect tumor cells

Question 8

What is immunogenicity?

Answer 8

The ability of the immune cells to generate an immune response

Question 9

How can immunoediting happen in 3 sequential phases?

Answer 9

1. Elimination - immuno-surveillance to detect + destroy
2. Equilibrium - immune system controls net growth
3. Escape -

Question 10

What are cytokines associated with?

Answer 10

Strong anticancer responses
T helper cells 1 and cytotoxic T cell responses

Question 11

How do monoclonal antibodies work?

Answer 11

bind to growth receptors and interfere with signalling pathways