CHD AND ANTI-ANGINA AGENTS

Question 1

What is angina pectoris?

Answer 1

The symptoms of angina pain is the response to the reduced coronary blood flow in the heart
Associated with angina pain

Question 2

What does the left coronary heart supply?

Answer 2

Supplies the left and right heart

Question 3

What does the right coronary heart supply?

Answer 3

Supplies the SAN and AVN and the right heart which control the HR and involved in the propagation of excitation through the heart

Question 4

How does venous blood return?

Answer 4

Via the RA via the doorway sinus and anterior cardiac vein
The heart chambers directly via thebesian veins
Presence of collateral vessels

Question 5

What is the underlying cause of angina pectoris or stable angina?

Answer 5

Atheromatous disease of the coronary arteries

Question 6

What is the main symptom of angina?

Answer 6

Chest pain - feeling tight, dull or heavy - although may have a sharp stabbing pain
Spreads to your left arm, neck, jaw or back
Stops within a few mins of resting can be triggered by exercise or stress

Question 7

What are the other angina symptoms?

Answer 7

SOB
Feeling sick (nausea)
Pain in lower chest or belly
Feeling very tired

Question 8

What are the therapeutic strategy for treatment of stable angina?

Answer 8

Reduce oxygen demand - reduce HR and cardiac preload
Increase oxygen supply - increase coronary blood flow - use drugs
Increase regional collateral blood flow