Colesterol Flashcards

1
Q

La mayoría de la síntesis de colesterol se produce en qué órgano

A

Hígado

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2
Q

En qué parte de la célula sucede la síntesis de colesterol en

A

CITOPLASMA Y REL

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3
Q

Precursor de síntesis de colesterol

A

Acetil coa

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4
Q

De dónde provienen todos los carbonos del colesterol

A

Del Acetil CoA

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5
Q

Nombre de la síntesis de colesterol

A

Colesterogenesis

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6
Q

Enzima marcapaso de la síntesis de colesterol

A

HMG COA REDUCTASA
Hidroxilo metil glutaril CoA reductasa

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7
Q

En dónde está ubicada la HMG COA reductasa

A

En membrana de REL

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8
Q

Qué reacción cataliza la HMG COA reductasa

A

Síntesis de ácido MEVALONICO

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9
Q

La HMG COA REDUCTASA, es regulada por fosforilacion desfosforilacion

A

Desfosforilacion(insulina +): la activa
Fosforilacion (glucagon-): Baja actividad

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10
Q

Regulación de la HMG CoA reductasa por alosterismo negativo

A

Colesterol: negativo

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11
Q

Destino del colesterol

A

Síntesis de ácidos biliares
Recambio membrana
Excreción bilis
Exportación a tejido

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