Random high yield facts Flashcards

1
Q

Ix for cellulitis?

A

Diagnosis can be made clinically

FBC (WCC) , ESR, CRP
wound swab
blood cultures
USS for DVT
Xray for osteomyelitis

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2
Q

risk factors for cellulitis?

A

breaks in skin / trauma
diabetes
immunocompromise
IVDU
venous insufficiency

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3
Q

complications of cellulitis?

A

necrotising fasciitis - hosp for IV abx and debridement
osteomyelitis
sepsis

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4
Q

Prophylaxis for contacts in meningitis?

A

if close contact within 7 days - ciprofloxacin
no prophylaxis if pneumococcal meningitis

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5
Q

Mx of chlamydia?
Gonorrhoea?
Syphilis?

A

chlamydia - doxycycline 7 days
gonorrhoea - IM ceftriaxone or oral cefixime + oral azithromycin if needle-phobic
syphilis - IM benzypenicillin

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6
Q

TB key mx steps?

A

2 months RIPE, 4 months RI
latent = 3 months RI or isoniazid for 6

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7
Q

causes of nephritic syndrome?

A

GRIP

Goodpastures
Rapidly progressive glomerulonephritis
IgA nephropathy
Post streptococcal glomerulomephritis

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8
Q

causes of nephrotic syndrome?

A

diabetic nephropathy

MMF:
minimal change disease
membranous glomerulonephritis
focal segmental glomerulonephritis

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9
Q

Define CKD

A

a gradual decline in kidney function (eGFR) for over 3 months
Irreversible
Results in proteinuria

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10
Q

Define AKI

A

a sudden reversible decline in kidney function over hours - weeks
results in raised creatinine and oliguria

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11
Q

Risk factors for AKI?

A

CKD
heart failure
sepsis
increasing age (>65)
diabetes
use of contrast / nephrotoxic drugs

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12
Q

Causes of CKD?

A

APCKD
diabetes
hypertension
glomerulonephritis
renal vascular disease

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13
Q

Staging of CKD?

A

eGFR
stage 1 : >90
stage 2 : <90-60
stage 3a: 59 - 45
stage 3b : 44 - 30
stage 4 : 29 - 15
stage 5 : 14- 0

proteinuria:
stage 1 : less than 3mg/mmol
stage 2: 3 - 30 mg/mmol
stage 3: 30 + mg/mmol

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14
Q

Staging of AKI?

A

stage 1 : 0. 5 ml/kg of urine for 6-12 hours
1.5 - 1.9 x baseline creatinine

stage 2 : 0. 5 ml/kg for 12-24 hours
2 x baseline creatinine

stage 3 : 0.3ml/kg for >24 hours or anuria for 12 hours
3 x baseline creatinine

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15
Q

Complications of glomerulonephritis?

A

DVT
CKD
hypertension and hyperlipidaemia

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16
Q

Mx of glomerulonephritis?

A

steroids, blood pressure control, LMWH for DVT

17
Q

Basic steps in mx of meningitis?

A

IV antibiotics:
3 months - 50 yrs: cefotaxime (or ceftriaxone)
> 50 yrs: cefotaxime + amoxicillin for adults

IV dexamethasone : don’t give if post surgery or meningococcol (rash)

18
Q

Bloods in meningitis?

A

full blood count
renal function
glucose
lactate
clotting profile
CRP

19
Q

What should CSF be tested for in meningitis?

A

glucose, protein, microscopy and culture
lactate
meningococcal and pneumococcal PCR
enteroviral, herpes simplex and varicella-zoster PCR
consider investigations for TB meningitis

20
Q

When should LP be delayed in meningitis?

A

signs of severe sepsis or a rapidly evolving rash
severe respiratory/cardiac compromise
significant bleeding risk
signs of raised intracranial pressure

21
Q

causes of AF?

A

hypertension
hyperthyroidism
pneumonia
mitral stenosis

22
Q

what is paroxysmal AF? mx?

A

episodes come and go, and usually stop within 48 hours without any treatment

DOAC if high CHADS-VASc
flecainide ‘pill in pocket’

23
Q

Complications of CKD?

A

bone mineral disease
IDA
AKI
acidosis and hyperkalaemia
IHD

24
Q

Investigations for CKD?

A

FBC, U&Es, CRP
bone profile
diabetes screen - Hba1c and BM
BP
USS for APCKD, renal biopsy
autoantibodies for lupus

25
Q

complications of renal transplant?

A

rejection
disease recurrence
CVD
opportunistic infection
SCC

26
Q

causes of AKI?

A

pre renal :
dehydration
hypotension
heart failure

renal:
glomerulonephritis
interstitial nephritis
ATN

post renal:
BPH, stones , cancer, strictures

27
Q

Ix for AKI? Mx?

A

urinalysis, monitor urine output, USS KUB

Mx: fluid resus, stop nephrotoxic meds, relieve obstruction e.g. insert catheter

28
Q

complications of AKI?

A

progression to CKD
fluid overload, HF, pulmonary oedema
hyperkalaemia
metabolic acidosis
uraemia (encephalopathy, pericarditis)