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MTAP 2 - FINALS - RATIO > HEMA2 > Flashcards

HEMA2 Flashcards

1
Q

It measures the time required to generate
thrombin and fibrin polymers via intrinsic
pathway:

A

APTT

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2
Q

The following are negatively charged particulate
activator used in APTT except:

A

THROMBIN

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3
Q

An increased in APTT will affect the following
coagulation factor, Except:

A

FVII

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4
Q

Determines the rate of thrombin-induced
cleavage of fibrinogen to fibrin monomers and
subsequent polymerization of hydrogen bonded polymers:

A

TT

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5
Q

It is also known as the plasma thromboplastin
antecedent:

A

FXI

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6
Q

It is also known as the plasma thromboplastin
component:

A

FIX

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7
Q

The following coagulation factor are consumed
during the process of coagulation, except

A

FXII

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8
Q

Which of the following coagulation factor is
inhibited by warfarin?

A

FIX

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9
Q

The specimen if a patient with prolong APTT was subjected to a mixing study shows correction of APTT after immediate mixing but no correction after a 2-hour incubation was possibly indicated by:

A

VIII INHIBITOR

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10
Q

This procedure is used to monitor oral
anticoagulant therapy, a screening test in
diagnosis of coagulation deficiencies and a
component of liver profile assessment.

A

PT

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11
Q

It involves the principle of adding of plasma to an excess of extrinsic thromboplastin-calcium
substrate. The following coagulation factor
therefore is being detected by this test, except:

A

FIX

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12
Q

Which of the following coagulation factor is not
consumed during the process of coagulation?

A

FXI

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13
Q

Which of the following coagulation factor will be
most likely affected if the patient has vitamin K
deficiency?

A

FIX

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14
Q

Anti-FVII inhibitor is usually associated with?

A

BLEEDING

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15
Q

This test is used to identify and quantitate
deficiencies in the intrinsic clotting system and
to control anticoagulant therapy:

A

PTT

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16
Q

The following coagulation factor are consumed
during the process of coagulation, except:

A

PROCONVERTIN

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17
Q

The following are calcium and vitamin K
independent coagulation factors, except:

A

PTC

18
Q

The following are considered as serine proteases, except:

A

LABILE FACTOR

19
Q

Which of the following will serve as an activator
in prothrombin time test?

A

NEITHER

20
Q

The following are calcium and vitamin K
dependent coagulation factor, except:

A

PTA

21
Q

The component of the APTT reagent which will
activate the contact factor in intrinsic pathway:

A

PF3

22
Q

Which of the following will serve as the source of tissue factor:

A

BOTH

23
Q

The primary in vivo initiation mechanism for
extrinsic coagulation cascade depends on the
formation of:

A

TF:VIIa

24
Q

When a person has Vitamin K deficiency, the
following coagulation factor will most likely be
affected, except:

A

E

25
Q

It is considered the marker of thrombosis and
fibrinolysis:

A

FRAGMENT D-D

26
Q

The component of the APTT reagent which is
required to activate the prothrombin in the
common pathway:

A

CALCIUM CLORIDE

27
Q

A subtype of Von Willebrand Disease
characterized by mutations within the A1
structural domain of Von Willebrand Factor
molecules:

A

SUBTYPE 2B VON WILLEBRAND DISEASE

28
Q

A subtype of Von Willebrand Disease
characterized by an autosomal point mutation in the A2 and D1 structural domains of the Von
Willebrand Factor molecules.

A

SUBTYPE 2A VON WILLEBRAND DISEASE

29
Q

A subtype of von Willebrand Disease
characterized by an autosomal VWF gene
missense mutation in the D9 domain of the von
Willebrand factor molecule.

A

SUBTYPE 2N VON WILLEBRAND DISEASE

30
Q

A subtype of von Willebrand disease
characterized by a qualitative VWF variant that
possesses poor platelets receptor binding site
generating a normal multimeric distribution
pattern in electrophoresis.

A

SUBTYPE 2M VON WILLEBRAND DISEASE

31
Q

APTT: Prolonged
PT: Prolonged
Aged Serum: Not Corrected
Age Plasma: Not Corrected
Adsorbed plasma: Corrected

A

E

32
Q

APTT: Prolong
PT: Prolong
Aged Serum: Not Corrected
Fresh Serum: Corrected
Aged Plasma: Corrected

A

STUART FACTOR

33
Q

APTT: Prolong
PT: Prolong
Aged Serum: Not Corrected
Fresh Serum: Not Corrected
Aged Plasma: Corrected

A

FIBRINOGEN

34
Q

PTT: Prolong
PT: Prolong
Adsorbed Plasma: Not corrected
Fresh Plasma: Corrected
Aged Plasma: Corrected

A

PROTHROMBIN

35
Q

APTT: Prolong
PT: Prolong
Fresh Serum: Corrected
Aged Serum: Corrected
Aged Plasma: Not Corrected

A

LABILE
FACTOR

36
Q

APTT: Prolong
PT: Normal
Aged Plasma: Corrected
Adsorbed Plasma: Corrected
Aged Serum: Corrected

A

E

37
Q

APTT: Prolong
PT: Normal
Fresh Serum: Not Corrected
Aged Plasma: Not Corrected
Adsorbed Plasma: Corrected

A

ANTIHEMOPHILIC FACTOR A

38
Q

APTT: Prolong
PT: Normal
Adsorbed plasma: Not Corrected
Fresh Serum: Corrected
Aged Serum: Corrected

A

PLASMA THROMBOPLASTIN COMPONENT

39
Q

APTT: Prolong
PT: Normal
Aged Serum: Not Corrected
Fresh Plasma: Corrected
Adsorbed Plasma: Corrected

A

ANTIHEMOPHILIC FACTOR A

40
Q

APTT: Prolong
PT: Normal
Adsorbed plasma: Not Corrected
Aged Serum: Corrected
Aged Plasma: Corrected

A

CHRISTMAS
FACTOR

MTAP 2 - FINALS - RATIO (6 decks)

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