Infections - My Cards Flashcards

1
Q

When should you refer conjunctivitis?

A

Eye pain
Headache or photophobia
Under 2 years
Contact lenses
Reduced visual acuity

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2
Q

What monitor is required for clindamycin?

A

Platelets - thrombocytopenia
Liver and renal function if using for over 10 days

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3
Q

What are the severe side effects of clindamycin?

A

Thrombocytopenia
C.Diff
SJS

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4
Q

What activity does linezolid have?

A

Gram positive including MRSA and VRE

No gram negative activity

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5
Q

What is the safety advice with linezolid? (2)

A

Optic neuropathy if used for more than 28 days
Blood disorders - weekly FBC

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6
Q

What are the contraindications for linezolid?

A

Adrenal tumours and thyroitoxicosis
Bipolar and schizophrenia
Uncontrolled hypotension

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7
Q

What are the key interactions for linezolid?

A

MAIOs (or used within 2 weeks)
SSRIs and TCAs - hypertensive crisis (serotonin syndrome)

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8
Q

What are the key side effects for trimethoprim?

A

Hyperkalaemia
Fungal overgrowth
SJS
Blood disorders

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9
Q

What is the interaction between trimethoprim and warfarin?

A

Increase warfarin levels - monitor INR

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10
Q

Why should oral preparations of vancomycin be avoided in systemic infections?

A

Not well absorbed (therefore oral preparations are good for C.diff

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11
Q

What are the key side effects for vancomycin? (5)

A

Red man syndrome
Thrombophlebitis- infusion site reaction
Ototoxicity
Nephrotoxicity
Thrombocytopenia

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12
Q

Which tetracycline has a very broad spectrum?

A

Minocycline

But rarely used due to irreversible pigmentation and risk of lupus-erythematosus-like syndrome

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13
Q

What condition are all tetracyclines contraindicated?

A

Myasthenia gravis

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14
Q

Which tetracyclines can cause oesophageal irritation?

A

Doxy
Mino
Tetra

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15
Q

Which tetracyclines interact with milk?

A

Demo
Oxy
Tetra

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16
Q

Which tetracyclines cause photosensitivity?

A

Doxy
Demo

17
Q

What antibiotics can be used in UTI in pregnancy?

A

Nitrofurantoin (avoid @ term)
Amoxicillin
Cefalexin

For 7 days

18
Q

When is the MMR vaccine given?

A

Age 1

Booster @ 3 years and 4 months

19
Q

When are the 1st three sets of vaccinations given in children?

A

8, 12, and 16 weeks

20
Q

When is the MenB vaccine given?

A

8 and 16 weeks

Boosted @ 1 year

21
Q

When is the MenACWY vaccine given?

A

14 years

22
Q

What abx should be given for scarlet fever and how long for?

A

1st phenoxymethylpenicillin for 10 days
2nd Clarithromycin fir 5 days

23
Q

What are the symptoms of scarlet fever?

A

Sandpaper rash
Strawberry tongue with white coating that peels off

24
Q

How long should ear infections be treated for?

A

7 days

25
Q

What is 1st line for prostatitis?

A

Ciprofloxacin

2nd = levofloxacin

26
Q

How long should you treat prostatitis for?

A

14 days then review

27
Q

What can be used as 2nd like for UTIs in non-pregnant women?

A

Pivmecillinam or fosphomycin

28
Q

What antibiotics can be used for recurrent UTIs?

A

Nitrofurantoin
Trimethoprim
Amoxicillin
Cefalexin

29
Q

How should you treat oral candidiasis? What are the doses?

A

Miconazole 2.5ml QDS after food

Nystatin 1ml QDS (half in each side)

Fluconazole capsules 100mg OD

All for 7 days (or continue for 2 days after resolved - not Fluconazole)

30
Q

How should you treat C.Diff?

A

Vancomycin 125mg QDS for 10 days

31
Q

How should you treat H.pylori? What are the doses?

A

PPI
PLUS
Amoxicillin 1g BD
PLUS
Clarithromycin 500mg BD
OR
Metronidazole 400mg BD

For 7 days

32
Q

What is 1st line for acute diverticulitis?

A

Co-amoxiclav

Cefalexin AND metronidazole if penicillin allergic

For 5 days

33
Q

How is chlamydia treated?

A

1st = doxycycline 100mg BD for 7 days
2nd = azithromycin 1g stat then 500mg BD for 2 days

34
Q

What is 1st line for bacterial vaginosis?

A

Metronidazole tablets
OR
Clindamycin 2% cream

Treat for 7 days