Regulation of Cardiac Output and Blood Pressure Flashcards

1
Q

Preload can become raised due to

A

Fast filling time and increased venous return

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2
Q

Contractility can become raised due to

A

Sympathetic stimulation
Epi and norepi
high intracellular calcium ions
high blood calcium levels
thyroid hormones
glucagon

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3
Q

Afterload can become raised due to

A

Increased vascular resistance
Semilunar valve drainage

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4
Q

Preload can be decreased due to

A

decreased thyroid hormones
decreased calcium ions
high or low potassium ions
high or low sodium
low body temperature
hypoxia
abnormal pH balance
drugs

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5
Q

Contractility can become lowered due to

A

Parasympathetic stimulation
acetylcholine
hypoxia
hyperkalemia

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6
Q

Afterload can become lowered due to

A

Decreased vascular resistance

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7
Q

What factors affect heart rate?

A

Increase (Positive chronotrope)-
Sympathetic input
Hormones, such as thyroid hormone

Decrease (Negative chronotrope)-
Parasympathetic input

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8
Q

Total Peripheral Resistance is a product of these three factors

A

Blood viscosity
Total blood vessel length
Vessel diameter (main factor)

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9
Q

The amount of blood ejected by each ventricle in 1 minute is

A

Cardiac output

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10
Q

Equation(s) for CO

A

CO = HR x SV
CO = BP / TPR

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11
Q

There are four main factors that affect the CO

A

Heart Rate
Contractility
Preload
Afterload

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12
Q

Equation for Blood pressure

A

BP = CO x TPR

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13
Q

The SA node is the _____ mechanism for controlling CO.

A

Intrinsic

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14
Q

Neural control of CO and BP (extrinsic)

A

Rapid: Neural control of vessel diameter, heart rate, stroke volume

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15
Q

Chemical/hormone control of CO and BP (extrinsic)

A

Intermediate to long-term:
Renin-Angiotensin II system
Renin-Aldosterone system
Antidiuretic Hormone (ADH)

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16
Q

Three areas of the vasomotor center (neural control)

A

Vasoconstrictor
Vasodilator
Sensory

17
Q

Vasoconstrictor Area- Neurons originating here extend down the spinal cord and ____

A

excite preganglionic sympathetic fibers.

18
Q

The Sensory Area is Located in the ___

A

Nucleus of Tractus Solitarius

19
Q

When needed, the lateral portions of the Vasomotor center transmit _____ to increase heart rate and contractility

A

excitatory impulses through the sympathetic nerve fibers

20
Q

Through the Autonomic Nervous System, the Vasomotor Center regulates these three things

A

HR, SV, and TPR

21
Q

Sensory info from ____ receptors enters the Nucleus of Tractus Solitarius from ___ and ___

A

Baroreceptors; Glossopharyngeal and vagus

22
Q

The rate of firing from the baroreceptors progressively ____ with increasing blood pressure

A

increases

23
Q

The Baroreceptor Reflex results in _____ by decreasing sympathetic outflow and increasing parasympathetic outflow from the CNS

A

decreased blood pressure

24
Q

When arterial blood pressure falls well below normal, these receptor cells are hypoperfused, resulting in low O2, elevated CO2, and elevated H+. Signals are transmitted via the glossopharyngeal and vagus nerves which excite the Vasomotor Center

A

Chemoreceptors

25
Q

Chemoreceptors increase BP due to

A

increased TPR and increased CO

26
Q

What is the CNS Ischemic Response?

A

Decreased blood flow due to hypotension results in increasing levels of CO2 and H+ in the medulla, This has a direct effect of stimulating the sympathetic fibers in the Vasomotor Center, resulting in an increase in blood pressure.

27
Q

In the RAA System, _____ in the walls of the Afferent Arterioles act as baroreceptors and respond to a drop in blood pressure by releasing Renin

A

Juxtaglomerular cells