Week 1 and 2 topics Flashcards

1
Q

any substance (except
food and water) when taken into
the body alters the body’s
function either physically and/or
psychologically

Therapeutic agent; any substance, other than
food, used in the prevention, diagnosis,
alleviation, treatment, or cure of disease.
* A substance recognized by an official
pharmacopoeia or formulary. A substance
intended for use in the diagnosis, cure,
mitigation, treatment, or prevention of
disease. A substance (other than food) intended to
affect the structure or any function of the body.

A

Drug

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2
Q

:A finished dosage
form, for example, a tablet, capsule or
solution that contains an active
pharmaceutical ingredient, generally,
but not necessarily, in association with
inactive ingredients.

A

Pharmaceutical (product)

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3
Q

: any
substance or mixture of substances intended to be used in the
manufacture of a drug (medicinal) product and that, when used
in the production of a drug, becomes an active ingredient. They
produce pharmacological activity or other direct effect in
diagnosis, cure, mitigation, treatment or prevention of disease
or to affect the structure or function of the body.

A

Active Pharmaceutical Ingredient (API):

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4
Q

component of the finished product other than API,
examples are fillers, colorants, flavorants, solvents, preservatives.

A

Excipients:

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5
Q

Top 1-3 list of Top Pharmaceutical Companies in the Philippines

A

Top 1: Pfizer
top 2: AstraZeneca Philippines
top 3: Eli Lill and Company

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6
Q

Top 4-6 list of Top Pharmaceutical Companies in the Philippines

A

4: GlaxoSmithKline
5: Merck, Sharp and Dohme
6: Novartis

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7
Q

Top 7-10 list of Top Pharmaceutical Companies in the Philippines

A

7: Roche
8: Sanofi-Aventis Philippines
9: United Laboratories
10: Wyeth

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8
Q

Others list of Top Pharmaceutical Companies in the Philippines

A

Abbott
Johnson &Johnson
Boehringher Ingelheim
Bristol Myers Squibb
Bayer
Pascual Laboratories
Schering Plough
InnoGen Pharma Group Inc
Natrapharm
GV International
Euro-Med Lab
Baxter TC Pharma Ind.
International Pharma
Getz Pharma
Interphil Laboratories

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9
Q

other term for Prescription Drug?

A

Ethical Drugs

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10
Q

Top 1-10 Prescription Drug Brands

A

1: Novarsc [Pfizer]
2: Ventolin [Glaxo-SK]
3: Plavix [Sanofi-Aventis]
4: Augmentin [Glaxo-SK]
5: Neobloc [GX International]
6: Lipitor[Pfizer]
7: Tazocin [Wyeth]
8: Zegen [United American UL]
9: plendil [AstraZeneca]
10: Seretide [Glaxo-SK]

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11
Q

Novarsc [Pfizer] Indication and Generic name ?

A

: Hypertension
: Amlodipine

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12
Q

Ventolin [Glaxo-SK] indication and Generic name ?

A

: Asthma
: Albuterol/ salbutamol

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13
Q

Plavix [Sanofi-Aventis] indication and Generic name?

A

: Thrombosis/ Anti-platelet
:Clopidogrel

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14
Q

Augmentin [Glaxo-SK] indication and Generic name?

A

: Infection/ Antibiotic
: Amoxicillin / Clavulanic acid

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15
Q

Neobloc [GX International] indication and Generic name?

A

:Hypertension
: metoprolol

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16
Q

Lipitor[Pfizer] indication and Generic name?

A

:hypercholesterolemia/ Anti-cholesterol
: Atorvastatin

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17
Q

Tazocin [Wyeth] indication and Generic name?

A

: infection
:tazobactam

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18
Q

Zegen [United American UL] indication and Generic name?

A

: infection
: Cefuroxime axetil

19
Q

plendil [AstraZeneca]

A

:Hypertension
: Felodipine

20
Q

Seretide [Glaxo-SK] Indication and Generic name ?

A

: Asthma
:Salmeterol + Fluticasone

21
Q

Generic name of Xenical?

A

Orlistat

22
Q

Top 1-10 OTC BRAND in PH

A

1: Ceelin [Pediatrica]
2: Solmux [Westmont]
3: Neozep [Myra]
4: Biogesic [Biomedis]
5: Enervon [United American]
6: Alaxan [Therapharma]
7: Myra E [Myra]
8: Xenical [Roche]
9: Centrum [Wyeth]
10: Cherifer [Gx Pharma]

23
Q

Ceelin
Enervon
Myra E
Centrum
Cherifer

OTC drugs indication?

A

vitamin Supplement

24
Q

Does OTC drug Neozeop have potential to increase blood pleasure?

A

true

25
Q

a detailed examination of anything complex in
order to understand its nature or to determine its
essential features : a thorough study

A

Analysis

26
Q

defined as the application of analytical procedures used to
determine the purity, safety and quality of drugs and chemicals

  • A branch of chemistry, which involves the series of
    process for the identification, determination,
    quantitation, and purification.
  • This is mainly used for the separation of the
    components from the mixture and for the
    determination of the structure of the compounds
A

Pharmaceutical Analysis

27
Q

two main types of Analysis:

A

Qualitative And Quantitative

28
Q
  • What is in the sample?
    Identification
    Composition determination
    Ascertainment of impurities
A

Qualitative Chemistry

29
Q

How much is in the sample?
determination of the proportion of
components in a substance

A

Quantitative chemistry

30
Q

Analysis of purity and quality of drugs and chemicals used in practice.

Others: applied in throughout industry,
medicine, environment
- Analysis of the chemical
constituents found in human body.
- Analysis of medicinal agents and
their metabolites found in biological system

A

Qualitative–Quantitative
Chemistry in Pharmacy

31
Q

Classification of Analysis

A

Based on sample size
II. Based on the extent of determination
III. Based on nature of methods
IV. Based on materials used

32
Q

Based on sample size: < 1 mg

A

Ultramicroanalysis

33
Q

Based on sample size: 1 mg-– 10 mg

A

Microanalysis

34
Q

Based on sample size: 10 mg- 100mg

A

Semi-microanalysis

35
Q

Based on sample size: 100 mg – 1 g

A

Macroanalysis

36
Q

Based on the extent of
determination: Total amount of a class or a group of
active plant principles in a given
sample.

A

Proximate analysis

37
Q

Based on the extent of
determination: Amount of a specific constituent or a
single chemical species present in the
sample

A

Ultimate analysis

38
Q

Based on the nature of
methods: also known as general/ chemical/ wet/
stoichiometric method

A

Classical method

39
Q

Classical method examples?

A

titrimetric analysis
gravimetric analysis

40
Q

Based on the nature of methods: more accurate
* based on specific physical or
chemical properties of the analyte

A

Instrumental method

41
Q

Instrumental method: s—Works by measuring the
potential (volts) and/or current (amps) in an
electrochemical cell containing the analyte

A

Electrochemical methods

42
Q

Instrumental method:—based upon the measurement of the
interaction of the molecules with electromagnetic
radiation

A

Optical methods

43
Q

Instrumental method:It is defined as the process of
separation of the individual components of a mixture
based on their relative affinities towards stationary and
mobile phases.

A

Chromatography