Neiserria Flashcards

1
Q

are aerobic, nonmotile, non–spore-forming, gram-negative diplococci (pairs)

A

Neisseria spp.

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2
Q

Important species of the genus Neisseria are:

A
  1. N. meningitidis,
  2. N. gonorrhoeae,
  3. N. flavescens,
  4. N. subflava,
  5. N. sicca,
  6. N. mucosa,
  7. N. lactamica
  8. N. polysacchareae
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3
Q

are the primary human pathogens of the genus Neisseria and iron growth

A

Neisseria gonorrhoeae and neisseria meningitidis

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4
Q

Humans are the only natural host and meaning “Flow of seed”; Also known as “clap” from the French word clapoir meaning “brothel”

A

gonorrhea

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5
Q

Most commonly transmitted by sexual contact

A

Neisseria gonorrhoeae

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6
Q

Primary reservoir o n gonorrhoeae

A

Asymptomatic carrie

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7
Q

Incubation period of neisseria gonorrhoear

A

2-7 days

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8
Q

Clinical presentation

A
  • most common acute urethritis in men
  • purulent discharge and dysuria
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9
Q

Site of infection in n. Gonorrhoeae

A

Most common endocervix

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10
Q

Complication of n. Gonorrhoeae

A

Inflammatory disease

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11
Q

N. Gonorrhoeae It is inhibited by

A

Sodium polyanethol sulfonate

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12
Q

non-venereal infection is in the newborn (gonococcal eye infection)

A

Ophthalmia neonatorum

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13
Q

The eyes are coated with gonococci as the baby passes down the birth canal

A

Ophthalmia neontorum

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14
Q

Ophthalmia neonatorum can result

A

Blindness

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15
Q

Specimen collection preferred to used

A

Dacron or rayon swab

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16
Q

N. Gonorrhoeae transport media used

A

Amies medium with charcoal (within 6 hours)

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17
Q

Other term of perihepatitis

A

Fitz-Hugh-Curtis Syndrome

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18
Q

Medium of Choice of n. Gonorrhoeae

A

Chocolate agar plate

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19
Q

Selective medium of n. Gonorrhoeae

A
  1. Thayer-Martin
  2. Modified Thayer-Martin
  3. Martin-Lewis
  4. New York City
  5. GC-LECT
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20
Q

inhibits gram-positive bacteria, gram-negative ​​bacteria and fungi

A

Vancomycin and colistin

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21
Q

inhibits Proteus spp.

A

Trimethoprim

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22
Q

Incubation time of n. Gonorrhoeae

A

35 degree in 3-5% CO2

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23
Q

Nongonococcal Urethritis with organisms such as

A

Chlamydia trachomatis or ureaplasma urealyticum

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24
Q

Incubation is accomplished by use of

A

CO2 incubator or candle jar white wax only

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25
Q

CAP or Selective Agar colony morphology

A

small, gray to tan, translucent, and raised after 24-48 hours of incubation

26
Q

N. Gonorrhoeae oxidase test positive result

A

Purple

27
Q

traditional method for the identification of Neisseria spp.

A

Carbohydrate utilization

28
Q

meaning “Flow of seed”; Also known as “clap” from the French word clapoir meaning “brothel”

A

gonorrhea

29
Q

is added to neutralize the effects of SPS

A

Gelatin

30
Q

Specimens are collected from genitals or other sites, such as

A

Rectum, pharynx, and joint fluid

31
Q

Cell and colony Morphology of n. Gonorrhoeae

A

Cell: Aerobic, non-motile, non-spore forming, flat diplococci (kidney-like shape)

Colony: Small, gray to tan color, Translucent, Raised colonies

32
Q

Natural habitat of n. Gonorrhoeae

A

Commensals in Mucous Membrane Respiratory tract and urogenital tract

33
Q

N. Gonorrhoeae is only fermenter in

A

Glucose

34
Q

If the organism uses the particular carbohydrate what is the production

A

Acid production (yellow in color)

35
Q

It is an important etiologic agent of meningitis and meningococcemia

A

Neisseria meningitidids

36
Q

n. Meningitidis Can be found on the mucosal surfaces of the

A

Nasopharynx and oropharynx

37
Q

Mode of transmission of n. Meningitidis

A

Droplet

38
Q

Incubation period for n. Meningitidis

A

1-10 days

39
Q

• Frontal headache
• Stiff neck (nuchal rigidity)
• Confusion
• Photophobia
• 10-15% mortality rate; 10-20% neurologic complications or seizures

A

Meningitis

40
Q

• Frontal headache
• Stiff neck (nuchal rigidity)
• Confusion
• Photophobia
• 10-15% mortality rate; 10-20% neurologic complications or seizures

A

Meningitis

41
Q

Purpura (hemorrhaging of blood into the skin and mucous membranes producing bruises) with petechial skin rash (pinpoint red spot caused by hemorrhage)
• Tachycardia
• Hypotension
• Thrombosis
• In some cases, the disease becomes fulminant and spreads rapidly, causing:
- Disseminated intravascular coagulation,
- Septic shock
- Hemorrhage in the adrenal glands (Waterhouse-Friderichsen syndrome)

A

Meningococcemia

42
Q

Collection used in N. Meningitidis

A

Collection: CSF aspirate, Blood aspirate, Nasopharynx aspirate/swab, joint fluid; (uncommon) sputum aspirate, urogenital swab

43
Q

Meduim used n. Meningitidis

A

Sba and cap

44
Q

Cell Morphology of n. Meningitidis

A

Cell: Aerobic, non-motile, non-spore forming, flat diplococci (kidney-like shape)

Colony: Medium, gray, convex colonies
with green tinge when in SBA

45
Q

Antibiotic for Meningitis

A

Penicillin

46
Q

Antibiotic for meningococcemia

A

Third generation of cephalosporin

47
Q

Chemoprophylaxis of n. Meningitidis

A

Rifampin or ciprofloxacin/azithromycin

48
Q

Cell morphology of moraxella catarrhalis

A

Non-capsulated, non-motile, Assacharolytic
Smooth, opaque, Grayish to White color; “Hockey Puck” appearance, “Wagon Wheel” appearance

49
Q

Specimen collection of moraxella catarrhalis

A

Middle ear effusion, nasopharynx, sinus, sputum, bronchi

50
Q

Medium used in moraxella catarrhalis

A

Cap and sba

51
Q

Antibiotic for moraxella catarrhalis

A

Penicillin

52
Q

Most strains can tolerate lower temperature and grow well at in moraxella catarrhalis

A

Lower temperatures 28 Celsius

53
Q

“wagon-wheel” appearance in moraxella catarrhalis

A

Older colonies

54
Q

• misidentified as N. gonorrhoeae
• Non-glucose fermenter
• Grows on SBA
• Susceptible to colistin

A

N. cinerea

55
Q

• yellow-pigmented Neisseria species that is asaccharolytic

A

N. flavescens

56
Q

• large, very mucoid colonies (often adhere to the agar)

A

N. mucosa

57
Q

• glucose, maltose and lactose fermenter
• Misidentified as N. meningitidis (glucose and maltose fermenter only)

A

N. Lactamica

58
Q

• produces large amounts of extracellular polysaccharide when grown in media containing 1% or 5% sucrose

A

N. polysaccharea

59
Q

• dry, wrinkled, adherent, and breadcrumb-like colonies

A

N. sicca

60
Q

• dry, wrinkled, adherent, and breadcrumb-like colonies

A

N. sicca

61
Q

• “less yellow”

A

N. subflava

62
Q

• rod-shaped

A

N. elongata, N. weaveri, N. bacilliformis