CITOTOXICITY DEFECTS Flashcards

1
Q

What are the main cytotoxic cells?

A

NK cells
Cytotoxic T lymphocytes

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2
Q

How does it function the cytotoxicity process?

A

Cell-cell interaction
Cell conjugate formation
Docking
Exocytosis
Cytotoxic granules

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3
Q

What are the main mechanisms of target cell recognition of NK cells?

A

ADCC
Natural cytotoxicity

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4
Q

Main cytotoxicity defects

A

HLH
XLP

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