Prochlorperazine Flashcards
1
Q
Prochlorperazine Trade Name
A
Compazine
2
Q
Prochlorperazine Class
A
Antiemetic
Antipsychotic
3
Q
Prochlorperazine MOA
A
Dopamine antagonist (D2) inhibits communication from chemoreceptor trigger zone to the vomiting center of the brain; inhibits gastric SMC relaxation
Weak anticholinergic properties reduce migraine severity
4
Q
Prochlorperazine Onset/ Duration
A
Onset- 10-20 min
Duration- 4-12 hours
5
Q
Prochlorperazine Indications
A
Nausea/vomiting
Migraines
6
Q
Prochlorperazine Contraindications
A
Hypersensitivity
7
Q
Prochlorperazine Side effects
A
Bradychardia
Tachychardia
hypotension
CNS depression
sedation
drowsiness
blurred vision
akathisia
dystonia
8
Q
Prochlorperazine Adult Dose
A
5-10 IV/IO nausea/vomiting
10 IM migraine
9
Q
Prochlorperazine Pediatric Dose
A
Not recommended
