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VPH 122 (3rd exam) > Colibacillosis > Flashcards

Colibacillosis Flashcards

1
Q

severe form of colibacillosis in humans

A

severe hemorrhagic colitis

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2
Q

Is Colibacillosis asymptomatic for both humans and animals?

A

NO (animals only)

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3
Q

Colibacillosis is related to ____ diarrhea

A

Traveller’s diarrhea

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4
Q

In Davao del Norte, 3 out of 9 water sources tested positive for this group of bacteria

A

coliforms

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5
Q

50 acute diarrhea cases in Visayan region (Southern Leyte) after this typhoon

A

Typhoon Odette

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6
Q

difference of Commensal & Pathogenic E. coli?

A

exotoxins is present in Pathogenic

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7
Q

Intestinal pathogenic E. coli

[ PHITA Da ]

A

entero:
pathogenic
haemorrhagic
invasive
toxigenic
aggregative

Diffusely adherent

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8
Q

Extraintestinal pathogenic

[ USM ]

A

Uropathogenic
Sepsis-associacted
Meningitis-associated

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9
Q

• most zoonotic cases
• shiga-producing toxin

A

Entero: haemorrhagic
O157 : H7

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10
Q

E. coli in SMALL intestine

[ tpa ]

A

toxigenic
pathogenic
aggregative (+ large intestine)

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11
Q

E. coli in COLON

[ ih ]

A

invasive
haemorrhagic

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12
Q

heat stable & labile enterotoxin

A

ETEC
toxigenic

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13
Q

cytotoxic enterotoxin

A

EIEC
invasive

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14
Q

(2) attaching-effacing lesions

[ ph ]

A

EPEC & EHEC
pathogenic & haemorrhagic

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15
Q

destroys microvilli

A

EPEC
pathogenic

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16
Q

stacked brick appearance

A

EAEC
aggregative

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17
Q

undefined virulencr factor

A

DAEC
diffusely adherent

18
Q

Can Colibacillosis be killed with low/acidic pH?

A

NO
(it survives gastric acidity)

19
Q

How long does Colibacillosis shed in humans?

A

7 - 9 days or longer

20
Q

main transmission of Colibacillosis

A

feco-oral

21
Q

Colibacillosis is transmitted primarily from what animal meat?

A

Poultry meat

22
Q

Colibacillosis disease in man starts with colonization of ______

A

small & large intestine

23
Q

(2) disease of Colibacillosis in HUMANS

A
  1. Hemorrhagic Colitis
  2. Hemolytic Uremic Syndrome
24
Q

the disease in man with
• prodromal diarrhea
• acute kidney injury
• thrombonic thrombocytopenic purpura (elders)
- brain
- kidney

A

HUS

25
Q

swelling of blood vessels

A

hemor purpura

26
Q

is there CNS signs (man) in Colibacillosis?

A

YES

27
Q

(4) Animals affected with Colibacillosis?

A
  1. YOUNG ruminants
  2. Dogs
  3. Poultry (all ages)
  4. Birds
28
Q

Can coligranuloma of poultry be found in spleen?

A

NO
- liver
- cecum
- duodenum
- mesenterium

29
Q

Tranmission of Colibacillosis comes from meat of these 4 animals

A
  1. pigs
  2. horses
  3. fish
  4. POULTRY

others
- dairy

30
Q

What is the bacterial culture for Colibacillosis?

A

1) Trypticase soy broth
2) Sorbitol-MacConkey agar + Phage typing

31
Q

most reliable molecular finger-printing technique

A

Pulsed field gel electrophoresis

32
Q

Detects O & H antigens of Colibacillosis

A

Immunological & Nucleic acid-based rapid test

33
Q

Treatment to “avoid” HUS & TTP?

A

Fluid & Electrolyte replacement

34
Q

Can anti-motility drugs be recommended for Colibacillosis?

A

NO (contraindicated)

35
Q

Antimicrobial choice for Colibacillosis

[ EC NGT ]
eacy not gonna tell

A

Enrofloxacin
Cephalosporin

Neomycin
Gentamicin
TMPS

36
Q

Resistance for Colibacillosis

[ TSS ]
taylor swift swift

A

Tetracycline
Streptomycin
Sulfa drugs

37
Q

Treatment for humans “with” HUS / TTP (3)

A
  1. Dialysis
  2. Blood transfusion
  3. Plasmapheresis
38
Q

Animal with vaccine for Colibacillosis

A

Cattle

39
Q

Vaccine for cattle w/ Colibacillosis is against?

give:
dose -
route -
interval-

A

EHEC O157 : H7

2 dose
IM route
3 weeks apart

40
Q

Dose & weeks ap

A
41
Q

Can Colibacillosis be autoclaved?

A

YES

VPH 122 (3rd exam) (26 decks)

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